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(R)-3-((1-??????-2-?)??)-1H-??

(R)-3-((1-??????-2-?)??)-1H-??
(R)-3-((1-??????-2-?)??)-1H-?? ??? ???
?? ??:
143322-55-8
???:
(R)-3-((1-??????-2-?)??)-1H-??
???(??):
(R)-3-((1-??????-2-?)??)-1H-??
???:
(R)-3-((1-Methylpyrrolidin-2-yl)Methyl)-1H-indole
???(??):
Eletriptan IMP A;Eletriptan Impurity A;Eletriptan Impurity 8;Eletriptan Impurity 8 -13;(R)-3-((1-Methylpyrrolidin-2-yl)Methyl)-1H-indole;(R)- 3-[(1-Methyl-2-pyrrolidinyl)Methyl]-1H-Indole;1H-Indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-
CBNumber:
CB02623586
???:
C14H18N2
??? ??:
214.31
MOL ??:
143322-55-8.mol

(R)-3-((1-??????-2-?)??)-1H-?? ??

???
140-142°C
?? ?
365.0±15.0 °C(Predicted)
??
1.124±0.06 g/cm3(Predicted)
?? ??
-20°C Freezer
???
?????(?? ???), ???????(?? ???) ? ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
17.24±0.30(Predicted)
??
?? ??

??

(R)-3-((1-??????-2-?)??)-1H-?? C??? ??, ??, ??

??

(R)- 3-[(1-Methyl-2-pyrrolidinyl)methyl]-1H-Indole, is an impurity formed in the preparation of 5-Bromo-3-[(R)-1-methylpyrrolidn-2-ylmethyl]-1H-indole, an intermediate in the synthesis of Eletriptan which is used in the treatment of migraine.

(R)-3-((1-??????-2-?)??)-1H-?? ?? ?? ? ???

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(R)-3-((1-??????-2-?)??)-1H-?? ?? ??

???( 27)?? ??
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