ChemicalBook >?? ???? >CADP-???
CADP-???
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CADP-??? ??
- ?? ?
- 934.8±75.0 °C(Predicted)
- ??
- 2.57±0.1 g/cm3(Predicted)
- ?? ??
- -20°C
- ???
- DMSO (?? ???), ???(???????), ? (?? ???)
- ?? ?? (pKa)
- 0.97±0.70(Predicted)
- ??? ??
- ????? ??
- ??
- White to off-white
- ???? ??
- (Ovotestis from sea hare)
- ???
- ???
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
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CADP-??? C??? ??, ??, ??
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Cyclic adenosine diphosphate-ribose (cADPR) is an intracellular second messenger that mobilizes intracellular Ca2+ release from the sarcoplasmic reticulum through ryanodine receptors. CADPR is also a second messenger for glucose-induced insulin release from endocrine pancreas and for abscisic acid-induced calcium release in plants.??
ChEBI: A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors.Biochem/physiol Actions
Mobilizes intracellular Ca2+; regulates Ca2+-induced Ca2+?release specifically blocked by ryanodine; second messenger for glucose-induced insulin release from the endocrine pancreas and for abscisic acid-induced calcium release in plants.CADP-??? ?? ?? ? ???
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Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium
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CADP-??? ?? ??
???( 36)?? ??
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