????????
|
|
???????? ??
- ???
- 34-36 °C (lit.)
- ?? ?
- 143 °C (lit.)
- ??
- 1.757
- ???
- 1.4270
- ???
- 162 °F
- ?? ??
- Store below +30°C.
- ???
- ?????(?? ???), ???(?? ???)
- ?? ?? (pKa)
- 5.50±0.33(Predicted)
- ??? ??
- ??? ??? ??
- ??
- ???? ?? ??
- Specific Gravity
- 1.757
- ???
- ??
- BRN
- 1912584
- ???
- ????. ?? ???, ??, ? ???, ? ???? ???? ????.
- InChIKey
- XBNGYFFABRKICK-UHFFFAOYSA-N
- CAS ??????
- 771-61-9(CAS DataBase Reference)
??
- ?? ? ?? ??
| ??? ?? | Xi,T,C,Xn | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38-34-20/21/22-63-43-23/24/25-45-67-40 | ||
| ????? | 26-36-45-36/37/39-36/37-24/25-23-53 | ||
| ????(UN No.) | 2811 | ||
| WGK ?? | 3 | ||
| RTECS ?? | SM6680000 | ||
| F ?????? | 3 | ||
| ?? ?? ?? | Toxic/Irritant | ||
| TSCA | T | ||
| ?? ?? | 8 | ||
| ???? | III | ||
| HS ?? | 29081000 | ||
| ?? | LD50 scu-rat: 322 mg/kg IZSBAI 3,91,65 | ||
| ???? ?? | KE-27939 |
???????? C??? ??, ??, ??
??? ??
White solid??
Pentafluorophenol is used in the preparation of pentafluorophenyl esters for peptide synthesis and vulcanized polymers. It is also used for peptide coupling and heterocyclic acid derivatives. It is involved in the preparation of pentafluorophenyl formate which acts as a formulating agent for amines and amino acids.?? ??
Pentafluorophenol is widely used as a precursor in both solution and solid-phase peptide synthesis. It is also involved in the preparation of aromatic fluoro derivatives.Safety Profile
scu-rat LD50:322 mg/kg IZSBAI 3,91,65Purification Methods
Pentafluorophenol is a hygroscopic low melting solid not freely soluble in H2O. Purify it by distillation, preferably in a vacuum [Forbes et al. J Chem Soc 2019 1959, IR and pKa: Birchall & Haszeldine J Chem Soc 13 1959]. IRofafilmhas max 3600 (OH) and 1575 (fluoroaromatic breathing) cm-1 . The benzoyl derivative has m 74-75o, 3,4-dinitrobenzoyl derivative has m 107o, the tosylate has m 64-65o (from EtOH) and the K salt crystallises from Me2CO, m 242o(dec), with 1H2O-salt the m is 248o(dec) and the 2H2O-salt has m 245o(dec). [Beilstein 6 IV 782.]???????? ?? ?? ? ???
???
Ethanol, 2-[(2,4-dinitrophenyl)thio]-
1,3-Dioxane-5-carboxylic acid, 5-ethyl-2-oxo-, 2,3,4,5,6-pentafluorophenyl ester
???????
????????
MAC
Chloropentafluorobenzene
BIS(PENTAFLUOROPHENYL)CARBONATE
2,3,4,5,6-PENTAFLUOROBENZENEBORONIC ACID
2,3,4,5,6-Pentafluoroaniline
?????????-1,2-??
?????????
?????
?? ??
???????? ?? ??
???( 576)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Qi-Chem Co., Ltd. | +86-0411-88165951 +8613591335396 |
marketing@qi-chem.com | China | 133 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 |
abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12809 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 |
sales01@tairunfaz.com | China | 8051 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20235 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29730 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 |
info@dakenam.com | China | 19805 | 58 |
| Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 810 | 58 |
| Dongfan Chem. Co., Ltd. | 021-34500607 13391355195 |
sales@dfanchem.com | CHINA | 61 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21628 | 55 |
???????? ?? ??:
??????? ?????????????? 2-???? 4-????? ????? 4-?????? p-????? ???????? ????????
Penfluridol
Pentafluorobenzonitrile
PENTAFLUOROPHENYL ISOTHIOCYANATE
PENTAFLUOROPHENYL ISOCYANATE 97
PENTAFLUOROPHENYL CHLOROTHIONOFORMATE
9-FLUORENYLMETHYL PENTAFLUOROPHENYL CARBONATE
FMOC-GLY-OPFP
FMOC-CYS(TRT)-OPFP
N-Fmoc-N'-Trityl-L-histidine pentafluorophenyl ester