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15-?????????E2

15-?????????E2
15-?????????E2 ??? ???
?? ??:
26441-05-4
???:
15-?????????E2
???(??):
15-?????????E2
???:
15-KETO PROSTAGLANDIN E2
???(??):
15-KetoPGE2;15-Oxoprostaglandin E2;15-KETO PROSTAGLANDIN E2;15-Dehydroprostaglandin E2;Dinoprostone EP Impurity F;15-keto Prostaglandin E2 MaxSpecStandard;Alprostadil (Prostaglandin E1) Impurity 6;Alprostadil (prostaglandin E1) Impurity 14;15-keto Prostaglandin E2 Lipid Maps MS Standard;9,15-DIOXO-11ALPHA-HYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID
CBNumber:
CB0125323
???:
C20H30O5
??? ??:
350.45
MOL ??:
26441-05-4.mol

15-?????????E2 ??

?? ?
534.4±50.0 °C(Predicted)
??
1.144±0.06 g/cm3(Predicted)
?? ??
−20°C
???
DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2)
??? ??
??? ??
?? ?? (pKa)
4.75±0.10(Predicted)
??
White to off-white
??
  • ?? ? ?? ??
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
??????:
NFPA 704
0
2 0

15-?????????E2 C??? ??, ??, ??

??

15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 formed by 15-hydroxy PGDH. In vivo, 15-keto PGE2 is essentially inactive. It has an attenuated affinity for the EP4 and EP2 receptors compared to PGE2 (Ki = 2,600-15,000 nM for the inhibition of PGE2 binding compared to a Kd = 1 nM for PGE2).[Cayman Chemical]

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15-?????????E2 ?? ??:

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