(R)-1-(1H-イミダゾール-4-イル)-2-プロパンアミン 化學(xué)特性,用途語,生産方法
化學(xué)的特性
White to off-white solid
使用
R(-)-alpha-Methylhistamine is a potent agonist of the histamine H3-receptor.
定義
ChEBI: An aralkylamino compound that is histamine bearing a methyl substituent at the alpha-position (the R-enantiomer).
生物活性
Very potent, high affinity H 3?agonist (K D = 50.3 nM) that displays > 200-fold selectivity over H 4 receptors. Inhibits H 3 -mediated histamine synthesis and release in the CNS and stimulates H 4 -mediated eosinophil shape change (EC 50 = 66 nM). Also available as part of the Histamine H 3 Receptor Tocriset™ .
(R)-1-(1H-イミダゾール-4-イル)-2-プロパンアミン 上流と下流の製品情報
原材料
準(zhǔn)備製品