クロマノール293B 価格 もっと(4)

メーカー	製品番號(hào)	製品説明	CAS番號(hào)	包裝	価格	更新時(shí)間	購入
富士フイルム和光純薬株式會(huì)社(wako)	W01TOC1412	クロマノール293B Chromanol 293B	163163-23-3	10mg	￥63000	2024-03-01	購入
富士フイルム和光純薬株式會(huì)社(wako)	W01TOC1412	クロマノール293B Chromanol 293B	163163-23-3	50mg	￥264000	2024-03-01	購入
Sigma-Aldrich Japan	C2615	クロマノール293B ≥98% (HPLC), powder Chromanol 293B ≥98% (HPLC), powder	163163-23-3	10mg	￥49500	2024-03-01	購入
Sigma-Aldrich Japan	C2615	クロマノール293B ≥98% (HPLC), powder Chromanol 293B ≥98% (HPLC), powder	163163-23-3	50mg	￥213000	2024-03-01	購入

クロマノール293B 化學(xué)特性,用途語,生産方法

説明

Chromanol 293B is a blocker of slowly activating delayed-rectifier K⁺ current (I_Ks) with an IC₅₀ value of 6.89 μM in Xenopus oocytes expressing rat I_Ks channels. It is selective, having no activity at rat K_v1.1 or K_ir2.1 channels at a concentration of 30 μM. Chromanol 293B increases the rate and extent of I_Ks in guinea pig ventricular cells in a dose-dependent manner. It also inhibits cystic fibrosis transmembrane conductance regulator (CTFR) Cl^- currents (I_CTFR) with an IC₅₀ value of 19 μM in Xenopus oocytes expressing human CTFR.

使用

Chromanol 293B has been used in the inhibition of calcium and cyclic adenosine monophosphate (cAMP)-activated potassium channels in human epithelial cell lines. Chromanol 293B has been used in patch-clamp electrophysiology studies in cardiomyocytes.

一般的な説明

Chromanol 293B enantiomer is a potent inhibitor of potassium channel protein (KvLQT1). In human atrial myocytes, chromanol 293B inhibits repolarization potassium currents. Chromanol 293B improves glucose-stimulated insulin secretion (GSIS) in pancreas by modulating potassium voltage-gated channel (KCNQ1).

生物活性

Blocker of the slow delayed rectifier K + current (I Ks ) (IC 50 = 1-10 μ M). Also blocks the CFTR chloride current (I CFTR ) (IC 50 = 19 μ M).

クロマノール293B 上流と下流の製品情報(bào)

原材料

準(zhǔn)備製品

クロマノール293B 生産企業(yè)

名前	電話番號(hào)	電子メール	國籍	製品カタログ	優(yōu)位度
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32277	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	12952	65
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9803	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44813	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58

163163-23-3(クロマノール293B)キーワード:

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• 163163-23-3
• TRANS-N-[6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-METHYL-ETHANESULFONAMIDE
• CHROMANOL 293B
• 6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane
• N-[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-N-methylethanesulfonamide
• Chromagnol
• Ethanesulfonamide, N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-, rel-
• Chromanol 293B >=98% (HPLC), powder
• クロマノール293B
• 4-[エチルスルホニル(メチル)アミノ]-3-ヒドロキシ-3,4-ジヒドロ-2,2-ジメチル-2H-1-ベンゾピラン-6-カルボニトリル
• 2,2-ジメチル-3-ヒドロキシ-4-[メチル(エチルスルホニル)アミノ]-3,4-ジヒドロ-2H-1-ベンゾピラン-6-カルボニトリル
• N-(6-シアノ-3-ヒドロキシ-2,2-ジメチル-3,4-ジヒドロ-2H-1-ベンゾピラン-4-イル)-N-メチルエタン-1-スルホンアミド