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J113863

J113863 化學(xué)構(gòu)造式
353791-85-2
CAS番號(hào).
353791-85-2
化學(xué)名:
J113863
別名:
J113863
英語(yǔ)名:
1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
英語(yǔ)別名:
J 113863;1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE;CCR,Inhibitor,inhibit,rheumatoid,J-113863,CCR1,CCR3,CC chemokine receptor,Chemotaxis,collagen,arthritis,J 113863,J113863,CD18,anti-inflammatory
CBNumber:
CB72453425
化學(xué)式:
C30H37Cl2IN2O2
分子量:
655.44
MOL File:
353791-85-2.mol

J113863 物理性質(zhì)

貯蔵溫度 :
Store at +4°C
溶解性:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
外見(jiàn) :
Powder
色:
Light yellow to yellow

安全性情報(bào)

J113863 価格 もっと(3)

メーカー 製品番號(hào) 製品説明 CAS番號(hào) 包裝 価格 更新時(shí)間 購(gòu)入
富士フイルム和光純薬株式會(huì)社(wako) W01TOC2595 J113863
J 113863 		353791-85-2 1mg ￥38000 2024-03-01 購(gòu)入
富士フイルム和光純薬株式會(huì)社(wako) W01TOC2595 J113863
J 113863 		353791-85-2 10mg ￥82000 2024-03-01 購(gòu)入
富士フイルム和光純薬株式會(huì)社(wako) W01TOC2595 J113863
J 113863 		353791-85-2 50mg ￥344000 2024-03-01 購(gòu)入

J113863 化學(xué)特性,用途語(yǔ),生産方法

使用

UCB 35625 is an antagonist of CCR1, which are receptors prevalent in chronic inflammatory processes. UCB 35625 displays antiarthritic activity and is also a selective antagonist of CCR3.

生物活性

Potent chemokine receptor 1 (CCR1) antagonist (IC 50 values are 0.9 and 5.8 nM for human and mouse CCR1 receptors respectively). Also displays high selectivity for human but not mouse CCR3 receptors (IC 50 values are 0.58 and 460 nM respectively). Improves paw inflammation, joint damage and dramatically reduces cell infiltration into joints in collagen-induced arthritis in mice. Isomer of UCB 35625 (1,4-trans-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidiniumiodide ).

J113863 上流と下流の製品情報(bào)

原材料

準(zhǔn)備製品

J113863 生産企業(yè)

Global( 30)Suppliers
名前 電話番號(hào) 電子メール 國(guó)籍 製品カタログ 優(yōu)位度
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
 klq@cw-bio.com China 5944 55
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223;
 psaitong@jm-bio.com China 29774 58
Shanghai Universal Biotech Co.,Ltd 13774214275
 zhouzz@univ-bio.com China 24997 58
Kaifeng Mingren Pharmaceutical Co.,LTD 0371-65741762
sales@hasunny.com China 2380 58

353791-85-2(J113863)キーワード:

  • 353791-85-2
  • 1,4-CIS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
  • J 113863
  • CCR,Inhibitor,inhibit,rheumatoid,J-113863,CCR1,CCR3,CC chemokine receptor,Chemotaxis,collagen,arthritis,J 113863,J113863,CD18,anti-inflammatory
  • J113863
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