りんご酸アルモトリプタン
りんご酸アルモトリプタン 物理性質(zhì)
- 融點 :
- 170-172°C
- 貯蔵溫度 :
- 2-8°C
- 溶解性:
- 塩基性アルコール（微量）、DMSO（微量）、メタノール（微量、加熱）
- 外見 :
- 粉
- 色:
- 白からベージュ
- 水溶解度 :
- H2O: 10mg/mL, clear
りんご酸アルモトリプタン 価格
もっと(12)
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01MAS098156 |
りんご酸アルモトリプタン
Almotriptan malate |
181183-52-8 |
250mg |
￥341300 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01MAS098156 |
りんご酸アルモトリプタン
Almotriptan malate |
181183-52-8 |
1g |
￥757600 |
2024-03-01 |
購入 |
|
東京化成工業(yè)
|
A3111 |
りんご酸アルモトリプタン >98.0%(HPLC)
Almotriptan Malate
>98.0%(HPLC) |
181183-52-8 |
25mg |
￥9100 |
2024-03-01 |
購入 |
|
東京化成工業(yè)
|
A3111 |
りんご酸アルモトリプタン >98.0%(HPLC)
Almotriptan Malate
>98.0%(HPLC) |
181183-52-8 |
100mg |
￥21700 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
SML1210 |
≥98% (HPLC)
Almotriptan malate ≥98% (HPLC) |
181183-52-8 |
10mg |
￥23700 |
2024-03-01 |
購入 |
りんご酸アルモトリプタン 化學特性,用途語,生産方法
外観
白色～黃赤色～緑色粉末～結晶
効能
抗片頭痛薬, セロトニン受容體作動薬
説明
Almotriptan is an agonist of the serotonin (5-HT) receptor subtypes 5-HT
1B and 5-HT
1D (IC
50s = 12 and 13 nM, respectively, in a radioligand binding assay). It is selective for human 5-HT
1B and 5-HT
1D receptors over rat 5-HT
1A and human 5-HT
2A and 5-HT
4 receptors (IC
50s = 0.85, 25.1, and 140 μM, respectively). Almotriptan induces contractions in isolated canine saphenous veins (EC
50 = 394 nM) but not isolated rabbit renal or mesenteric arteries. It increases carotid vascular resistance in anesthetized cats (ED
100 = 11 μg/kg, i.v.) without increasing blood pressure or heart rate. Formulations containing almotriptan have been used in the treatment of migraine headaches.
化學的特性
Pale Yellow Solid
使用
Almotriptan is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.
定義
ChEBI: The malate salt of almotriptan.
一般的な説明
Almotriptan, marketed in 2000, has the highest oralbioavailability among all triptans. It is metabolizedby both MAO-A and CYP3A4, thus has a more favorableside effects profile when compared with sumatriptan.However, it is only available in a 12.5 mg tablet form.
りんご酸アルモトリプタン 上流と下流の製品情報
原材料
準備製品
りんご酸アルモトリプタン 生産企業(yè)
Global( 269)Suppliers
りんご酸アルモトリプタン スペクトルデータ(1HNMR)
181183-52-8(りんご酸アルモトリプタン)キーワード:
- 181183-52-8
- BUTANEDIOIC ACID, HYDROXY-, COMPD WITH 1-[[[3-[2-(DIMETHYLAMINO)ETHYL]-1H-INDOL-5-YL]METHYL]SULFONYL]PYRROLIDINE
- ALMOTRIPTAN MALATE
- AlmotriptanMaleate
- 1-[[[2-(Dimethyl-amino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine Malate
- 1-[[3-(2-dimethylaminoethyl)-5-indolyl]methanesulphonyl]pyrrolidine Malate
- LAS-31416 Malate
- Almotriptan
- 1-[[[3-[2-(dimeth
- 2-Hydroxy-butanedioic acid, compd. with N,N-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-indole-3-ethanamine (1:1)
- hydroxy-Butanedioic acid, compd.with 1-[[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine(1:1)(9CI)
- Almotriptan Malate (200 mg)
- AlMotriptan Malate
See: A575201
- AlMotriptan Malate (Axert)
- N,N-Dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine
- N,N-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-indole-3-ethanamine,compd. with 2-hydroxy-butanedioic acid
- Amotriptan malate
- Almogran
- Axert
- AXERT; ALMOGRAN; PNU-180638;PNU 180638
- PNU 180638
- PNU-180638
- Almotriptan Malate(PNU180638)
- 3-[2-(Dimethylamino)ethyl]-5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indole Malate
- ALMOTRIPTAN USP/EP/BP
- Almotriptan Malate (LAS 31416)
- Almotriptan MaleateQ: What is
Almotriptan Maleate Q: What is the CAS Number of
Almotriptan Maleate Q: What is the storage condition of
Almotriptan Maleate Q: What are the applications of
Almotriptan Maleate
- Almotriptan Malate (1013512)
- Butanedioic acid, 2-hydroxy-, compd. with N,N-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-indole-3-ethanamine (1:1)
- 1-[[[3-[2- (Dimethylamino) ethyl] - 1H- indol-5-yl] sulfonyl] pyrrolidine. Malate
- Almotriptan Malate, 10 mM in DMSO
- りんご酸アルモトリプタン