天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook >> CAS DataBase List >>4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride

4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride

CAS No.
35941-71-0
Chemical Name:
4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride
Synonyms
Fk 1160;RHC 2592;Solantal;Nsc289337;Corensoul;Nta-194 HCl;Usv 2592 HCl;benzo[d]thiazol-2(3H);Tiaramide hydrochloride;Tiaramide hydrochloride-r
CBNumber:
CB9941351
Molecular Formula:
C15H19Cl2N3O3S
Molecular Weight:
392.30066
MDL Number:
MFCD01702832
MOL File:
35941-71-0.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride Properties

Melting point 159-161°
Water Solubility Completely soluble in water
form powder to crystal
color White to Orange to Green
Merck 14,9424
FDA UNII ITY1616X9T

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Warning
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338-P310-P403-P501c
RTECS  TL7050000
HS Code  2934.20.8000
Toxicity LD50 in male mice, rats (mg/kg): 178, 203 i.v.; 298, 540 i.p.; 564, 3600 orally (Watanabe)

4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T3176 Tiaramide Hydrochloride >98.0%(T) 35941-71-0 25mg $123 2024-03-01 Buy
TCI Chemical T3176 Tiaramide Hydrochloride >98.0%(T) 35941-71-0 100mg $370 2024-03-01 Buy
TRC T445105 Tiaramide Hydrochloride 35941-71-0 1g $950 2021-12-16 Buy
AK Scientific 6762AL Tiaramide Hydrochloride 35941-71-0 25mg $357 2021-12-16 Buy
Chem-Impex 38322 Tiaramidehydrochloride,98%(AssaybyTitration) 98%(AssaybyTitration) 35941-71-0 100MG $740.32 2021-12-16 Buy
Product number Packaging Price Buy
T3176 25mg $123 Buy
T3176 100mg $370 Buy
T445105 1g $950 Buy
6762AL 25mg $357 Buy
38322 100MG $740.32 Buy

4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride Chemical Properties,Uses,Production

Originator

Solantal,Fujisawa,Japan,1975

Uses

Tiaramide Hydrochloride is a useful compound for treatment of gastrointestinal disease.

Definition

ChEBI: Tiaramide hydrochloride is a member of benzothiazoles.

Manufacturing Process

A solution of ethyl 5-chloro-2-oxo-3-benzo-thiazolineacetate (4.0 grams) in 1- (2-hydroxyethyl)piperazine is heated at 100°C for 24 hours. After cooling, the resulting mixture is extracted with chloroform. The chloroform extract is washed with water and shaken with 10% hydrochloric acid. The hydrochloric acid layer is washed with chloroform, made alkaline with 10% sodium hydroxide solution and extracted with chloroform. The chloroform extract is washed with water, dried over magnesium sulfate and concentrated. The residual oil (5.5 grams) is allowed to stand to form crystals, which are recrystallized from a mixture of ethyl acetate (40 ml) and ethanol (15 ml) to give 3-[4-(2-hydroxyethyl)-1-piperazinylcarbonylmethyl]-5-chloro-2(3H)- benzothiazolinone (3.2 grams) as colorless crystals, MP 159° to 161°C. The following is an alternate method of preparation: A mixture of 3-(1- piperazinyl)carbonylmethyl-5-chloro-2(3H)-benzothiazolinone (500 mg), anhydrous potassium carbonate (400 mg), 2-hydroxyethyl bromide (300 mg) and anhydrous ethanol (20 ml) is heated while refluxing for 5 hours. The reaction mixture is concentrated under reduced pressure. The residue is extracted with chloroform. The chloroform layer is dried over magnesium sulfate and concentrated. The residue is crystallized from a mixture of ethyl acetate and ethanol to give 3-[4-(2-hydroxyethyl]-1- piperazinylcarbonylmethyl]-5-chloro-2(3H)-benzothiazolinone (370 mg) as crystals, MP 159° to 160°C.

Therapeutic Function

Antiinflammatory

4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30231 58
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38630 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24529 81
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28387 80
Chengdu Kamel Pharmaceutical Co., Ltd 028-67136579 15828051124 sales@kamelpharm.com China 2123 55

View Lastest Price from 4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tiaramide hydrochloride pictures 2024-11-19 Tiaramide hydrochloride
35941-71-0
 US $80.00-233.00 / mg 98.48% 10g TargetMol Chemicals Inc.
1-Piperazineethanol, 4-[(5-chloro-2-oxo-3(2H)-benzothiazolyl)acetyl]-, monohydrochloride 4-[(5-Chloro-2-oxo-3-benzothiazolinyl)acetyl]-1-piperazineethanol hydrochloride Fk 1160 Nsc289337 Nta-194 HCl Tiaramide hydrochloride-r Usv 2592 HCl RHC 2592 5-Chloro-3-(2-(4-(2-hydroxyethyl)piperazin-1-yl)-2-oxoethyl)benzo[d]thiazol-2(3H)-one hydrochloride 5-Chloro-3-(2-(4-(2-hydroxyethyl) benzo[d]thiazol-2(3H) Tiaramide hydrochloride (JP14) Corensoul Solantal 4-[(5-chloro-2-oxo-2H-benzothiazol-3-yl)acetyl]piperazine-1-ethanol monohydrochloride Tiaramide hydrochloride 2(3H)-Benzothiazolone,5-chloro-3-[2-[4-(2-hydroxyethyl)-1-piperazinyl]-2-oxoethyl]-, hydrochloride(1:1) 1-Piperazineethanol, 4-[(5-chloro-2-oxo-3(2H)-benzothiazolyl)acetyl]- 5-Chloro-3-[[4-(2-hydroxyethyl)piperazin-1-yl]carbonylmethyl]-2-benzothiazolinone Hydrochloride Tiaramide hydrochloride, 10 mM in DMSO 35941-71-0 35941-70-0 C15H18ClN3O3SHCl