ANTI-TAP
- CAS No.
- Chemical Name:
- ANTI-TAP
- Synonyms
- ANTI-TAP;Anti-MEX67;Anti-DKFZp667O0311;Anti-Vesicle docking protein;Anti-Nuclear RNA export factor 1;ANTI-TRANSPORTER ASSOCIATED PROTEIN;Anti-NXF1 antibody produced in rabbit;Anti-VDP P115 antibody produced in goat;ANTI-TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING
- CBNumber:
- CB9202449
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01865352
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P305+P351+P338 |
ANTI-TAP price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA061593 | Anti-NXF1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $294 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB2501097 | Anti-VDP P115 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 100μg | $568 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA061593 | Anti-NXF1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $580 | 2024-03-01 | Buy | |
| Sigma-Aldrich | AV40639 | Anti-NXF1 antibody produced in rabbit IgG fraction of antiserum | 100μL | $443 | 2024-03-01 | Buy | |
| Sigma-Aldrich | AV40638 | Anti-NXF1 antibody produced in rabbit affinity isolated antibody | 100μL | $524 | 2024-03-01 | Buy |
ANTI-TAP Chemical Properties,Uses,Production
Uses
Anti-NXF1 polyclonal antibody is used to tag nuclear RNA export factor 1 protein for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of nuclear RNA export factor 1 in polyA-RNA nuclear export.
General Description
Nuclear RNA export factor 1 (NXF1, TAP) is a nuclear RNA exporter protein that contains a noncanonical RNP-type RNA binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. Nuclear RNA export factor 1 exports poly(A)+RNA from the nucleus into the cytoplasm.
Biochem/physiol Actions
NXF1 is one member of a family of nuclear RNA export factor. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. NXF1 overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.
ANTI-TAP Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-TAP Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Sai Ruirui Biotechnology Co., Ltd. | -- | sales@shrbio.com | CHINA | 6871 | 58 |
| Shanghai Beinuo Biotechnology Co., Ltd. | -- | beinuobio@163.com | CHINA | 6580 | 58 |
| Suzhou Ruinuode Biotechnology Co., Ltd. | -- | 2090855807@qq.com | CHINA | 6063 | 58 |
| Shanghai Hao Biological Technology Co., Ltd. | -- | market@xlswkj.com | CHINA | 6793 | 58 |
| Riedel-de Haen AG | -- | United States | 6773 | 87 | |
| BD Biosciences | -- | United States | 5013 | 82 | |
| Chemicon Internatinal, Inc. | -- | custserv@chemicon.com | United States | 4175 | 65 |
| BIODESIGN International/OEM Concepts | -- | info@biodesign.com | United States | 2376 | 50 |
| Rockland Immunochemicals Inc. | -- | info@rockland-inc.com | United States | 2043 | 76 |