Anticancer agent 105
- CAS No.
- 2450987-57-0
- Chemical Name:
- Anticancer agent 105
- Synonyms
- Anticancer agent 105
- CBNumber:
- CB914247346
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anticancer agent 105 Chemical Properties,Uses,Production
Uses
Anticancer agent 105 is a compound based on thienopyrimidine scaffold, with with good safety and anticancer properties. Anticancer agent 105 shows selective toxicity towards melanoma cancer, and induces apoptosis. And Anticancer agent 105 significantly inhibits the metastatic nodules, even in pulmonary metastatic melanoma mouse model[1].
in vivo
Anticancer agent 105 (compound 9cb) (9-9.5 mg/kg every 3rd d for 22 d; ip) inhibits metastatic nodules in B16-F10 melanoma-bearing C57BL/6 mice[1].
| Animal Model: | Pulmonary metastatic melanoma mouse model[1] |
| Dosage: | I: 9-9.5 mg/kg; II: 42-4.6 mg/kg |
| Administration: | IP; once daily every 3rd d for 22 d |
| Result: | Decreased the number of metastatic nodules in mouse. |
References
[1] Rogova A, et al. Synthesis of thieno[3,2-e]pyrrolo[1,2-a]pyrimidine derivatives and their precursors containing 2-aminothiophenes fragments as anticancer agents for therapy of pulmonary metastatic melanoma. Eur J Med Chem. 2023 Jun 5;254:115325. DOI:10.1016/j.ejmech.2023.115325
Anticancer agent 105 Preparation Products And Raw materials
Raw materials
Preparation Products
Anticancer agent 105 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19897 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19820 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from Anticancer agent 105 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-27 | Anticancer agent 105
2450987-57-0
|
US $0.00-0.00 / mg | 10g | TargetMol Chemicals Inc. |
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- Anticancer agent 105
2450987-57-0
- US $0.00-0.00 / mg
- TargetMol Chemicals Inc.