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ChemicalBook >> CAS DataBase List >>SULBENICILLIN

SULBENICILLIN

CAS No.
41744-40-5
Chemical Name:
SULBENICILLIN
Synonyms
SBPC;Kedacillina;Subenicillin;SULBENICILLIN;Sulbenicilina;(R)-Sulbenicillin;D-(-)-Sulbenicillin;Sulbenicillin, D-(-)-;a-Sulfobenzylpenicillin;SULBENICILLIN USP/EP/BP
CBNumber:
CB6715306
Molecular Formula:
C16H18N2O7S2
Molecular Weight:
414.45
MDL Number:
MFCD00869408
MOL File:
41744-40-5.mol
MSDS File:
SDS
Last updated:2022-12-21 16:56:50

SULBENICILLIN Properties

Melting point 197 °C (decomp)
Density 1?+-.0.1 g/cm3(Predicted)
pka 0.28±0.50(Predicted)
FDA UNII Q2VYF0562D
ATC code J01CA16

SULBENICILLIN price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0013659 SULBENICILLIN 98.00% 41744-40-5 1G $1709.4 2021-12-16 Buy
AvaChem 2843 Sulbenicillin 41744-40-5 10mg $39 2021-12-16 Buy
AvaChem 2843 Sulbenicillin 41744-40-5 25mg $59 2021-12-16 Buy
AvaChem 2843 Sulbenicillin 41744-40-5 100mg $129 2021-12-16 Buy
Product number Packaging Price Buy
API0013659 1G $1709.4 Buy
2843 10mg $39 Buy
2843 25mg $59 Buy
2843 100mg $129 Buy

SULBENICILLIN Chemical Properties,Uses,Production

Originator

Lillacillin,Takeda,Japan,1973

Definition

ChEBI: A penicillin antibiotic having a 6beta-[phenyl(sulfo)acetamido] side-chain.

Manufacturing Process

To a suspension of 1.08 parts by weight of 6-aminopenicillanic acid in 8 parts by volume of water is added 1.48 parts by weight of sodium bicarbonate. After the mixture is dissolved, a solution of 1.18 parts by weight of α-sulfophenylacetyl chloride in 10 parts by volume of diethylether is gradually added thereto. The mixture is stirred at a temperature in the neighborhood of 0°C for 1 hour. The aqueous layer is washed twice with 10 parts by volume of portions of ether and adjusted to pH 1.2 with cation exchange resin of polystyrene sulfonic acid type under constant cooling. Then the solution is washed twice with 15 parts by volume of portions of ethyl acetate, followed by extraction twice with 15 parts by volume of portions of n-butanol. The extracts are combined and washed twice with 15 parts by volume of portions of water and, then, extracted with an aqueous solution of sodium bicarbonate. The extract is adjusted to pH 6.5, washed with ether and lyophilized to give the sodium salt of α-sulfobenzylpenicillin. Yield is 1.2 parts by weight.

Therapeutic Function

Antibacterial

Antimicrobial activity

α-Sulfobenzylpenicillin, a semisynthetic penicillin supplied as the disodium salt. Its antimicrobial spectrum and pharmacokinetic pharmacokinetic behavior closely resemble those of carbenicillin. Following intravenous administration of 4 g, the mean plasma concentration at 1 h was approximately 160 mg/L, with a plasma elimination half-life of around 70 min. It is largely excreted in the urine, about 80% of the dose appearing in the first 24 h, less than 5% as the penicilloic acid. It has been noted that the penicilloic acid causes much stronger platelet aggregation than its parent. It is of very limited availability.

SULBENICILLIN Preparation Products And Raw materials

Raw materials

Preparation Products

SULBENICILLIN Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21631 55
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49732 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29808 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 7732 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD 		+86-0512-83500002 +8615195660023 sales@senfeida.com China 26362 58
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12335 58
Henan Jiuhua Biological Technology Co., Ltd. 15738884691 153248764872949584887 237654463 jiuhuabiochem@163.com China 2750 58

View Lastest Price from SULBENICILLIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SULBENICILLIN pictures 2019-12-26 SULBENICILLIN
41744-40-5
 US $1.00 / g 1g ≥98% g/kg/Ton Career Henan Chemical Co
  • SULBENICILLIN pictures
  • SULBENICILLIN
    41744-40-5
  • US $1.00 / g
  • ≥98%
  • Career Henan Chemical Co
SULBENICILLIN Subenicillin 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylsulfoacetyl)amino]-, [2S-[2a,5a,6b(S*)]]- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-phenylsulfoacetyl]amino]-, (2S,5R,6R)- (9CI) a-Sulfobenzylpenicillin D-(-)-Sulbenicillin SBPC Sulbenicillin, D-(-)- (2S,5β)-3,3-Dimethyl-7-oxo-6α-[[(R)-phenyl(sulfo)acetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid (R)-Sulbenicillin 6α-[(R)-Phenyl(sulfo)acetylamino]penicillanic acid (2S,5R,6R)-6-((S)-Carbamoyl(phenyl)methanesulfonoyl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenyl-2-sulfoacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenyl-2-sulfo-ethanoyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-7-keto-3,3-dimethyl-6-[(2-phenyl-2-sulfo-acetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-phenyl-2-sulfoacetyl]amino]-, (2S,5R,6R)- SULBENICILLIN USP/EP/BP Kedacillina Sulbenicilina 41744-40-5