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ChemicalBook >> CAS DataBase List >>(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE

CAS No.
148700-85-0
Chemical Name:
(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
Synonyms
L 733060;L-733,060 hydrochlor;L-733,060 HYDROCHLORIDE;3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine;Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)-;(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE
CBNumber:
CB6676120
Molecular Formula:
C20H19F6NO
Molecular Weight:
403.36
MDL Number:
MFCD05865535
MOL File:
148700-85-0.mol
Last updated:2023-05-04 17:34:33

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Properties

storage temp. 2-8°C
solubility DMSO: >10 mg/mL
form solid
color white
FDA UNII PK8CG2B44U

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0013970 L-733060 95.00% 148700-85-0 250MG $349.65 2021-12-16 Buy
Product number Packaging Price Buy
API0013970 250MG $349.65 Buy

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Definition

ChEBI: (2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidine is a member of piperidines.

Biological Activity

A potent antagonist of human tachykinin NK 1 receptors (K i values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze; orally bioavailable and brain penetrant.

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Shanghai Universal Biotech Co.,Ltd 13774214275 zhouzz@univ-bio.com China 24996 58
L-733,060 HYDROCHLORIDE (2S,3S)-3-[[3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY]-2-PHENYLPIPERIDINE HYDROCHLORIDE 3-((3,5-Bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine L 733060 Piperidine, 3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenyl-, (2S,3S)- L-733,060 hydrochlor 148700-85-0 Tachykinin receptor