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ChemicalBook >> CAS DataBase List >>tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

CAS No.
2375541-45-8
Chemical Name:
tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
Synonyms
187407;Autogramin-2;Autogramin-2,Inhibitor,inhibit,Autogramin2,Autophagy,Autogramin 2;tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate;Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-, 1,1-dimethylethyl ester
CBNumber:
CB65708228
Molecular Formula:
C21H27N3O4S
Molecular Weight:
417.52
MDL Number:
MFCD32174286
MOL File:
2375541-45-8.mol
Last updated:2024-11-13 11:39:26

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Properties

Density 1.252±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO (up t0 25 mg/ml) or in Ethanol (up to 25 mg/ml)
form solid
pka 7.59±0.20(Predicted)
color Off-white
Stability Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth BA171490 Autogramin 2 2375541-45-8 5mg $85 2021-12-16 Buy
Biosynth Carbosynth BA171490 Autogramin 2 2375541-45-8 10mg $135 2021-12-16 Buy
Biosynth Carbosynth BA171490 Autogramin 2 2375541-45-8 25mg $287.5 2021-12-16 Buy
Biosynth Carbosynth BA171490 Autogramin 2 2375541-45-8 50mg $472.5 2021-12-16 Buy
Biosynth Carbosynth BA171490 Autogramin 2 2375541-45-8 100mg $700 2021-12-16 Buy
Product number Packaging Price Buy
BA171490 5mg $85 Buy
BA171490 10mg $135 Buy
BA171490 25mg $287.5 Buy
BA171490 50mg $472.5 Buy
BA171490 100mg $700 Buy

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Chemical Properties,Uses,Production

Description

Autogramin-2 (2375541-45-8) is an inhibitor of autophagy (autophagy induced by amino acid starvation IC50 = 270 nM; Rapamycin IC50 = 140 nM) acting via selective targeting of the cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A).? Autogramin-2 inhibition of GRAMD1A inhibits biogenesis of the autophagosome.

References

References/Citations:

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
ChemShuttle, Inc. 0510-83588313-802 18800520310; sales@chemshuttle.com China 3002 62
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 lucy@atkchemical.com China 9952 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12306 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29774 58

View Lastest Price from tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Autogramin-2 pictures 2024-11-12 Autogramin-2
2375541-45-8
 US $38.00-113.00 / mg 96.25% 10g TargetMol Chemicals Inc.
  • Autogramin-2 pictures
  • Autogramin-2
    2375541-45-8
  • US $38.00-113.00 / mg
  • 96.25%
  • TargetMol Chemicals Inc.
tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate 187407 Autogramin-2 Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-, 1,1-dimethylethyl ester Autogramin-2,Inhibitor,inhibit,Autogramin2,Autophagy,Autogramin 2 2375541-45-8