salvigenin
- CAS No.
- 19103-54-9
- Chemical Name:
- salvigenin
- Synonyms
- Salvigenin Salvigenin;Salvigenin, 10 mM in DMSO;5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)chromen-4-one;5-Hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-;Salvigenin,inhibit,Apoptosis,immunomodulatory,ROS Kinase,Autophagy,Inhibitor,neuroprotective,antioxidant
- CBNumber:
- CB41375233
- Molecular Formula:
- C18H16O6
- Molecular Weight:
- 328.32
- MDL Number:
- MFCD00238678
- MOL File:
- 19103-54-9.mol
Melting point | 188 °C |
---|---|
Boiling point | 535.9±50.0 °C(Predicted) |
Density | 1.314±0.06 g/cm3(Predicted) |
storage temp. | 4°C, protect from light |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | powder |
pka | 6.33±0.40(Predicted) |
color | Yellow |
FDA UNII | V522YCM28A |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
NFPA 704 |
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salvigenin price More Price(18)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | S100700 | Salvigenin | 19103-54-9 | 10mg | $165 | 2021-12-16 | Buy |
TRC | S100700 | Salvigenin | 19103-54-9 | 100mg | $1320 | 2021-12-16 | Buy |
AK Scientific | W1622 | Salvigenin | 19103-54-9 | 10mg | $387 | 2021-12-16 | Buy |
ChemScene | CS-0016722 | Salvigenin 99.79% | 19103-54-9 | 10mg | $450 | 2021-12-16 | Buy |
Biosynth Carbosynth | FS66195 | Salvigenin | 19103-54-9 | 25mg | $500 | 2021-12-16 | Buy |
salvigenin Chemical Properties,Uses,Production
Uses
Salvigenin is a neuroprotective agent used in the treatment of neurodegenerative diseases acting through oxidative stress on cells.
Definition
ChEBI: Salvigenin is a trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups. It has a role as an autophagy inducer, an apoptosis inhibitor, an antilipemic drug, an immunomodulator, an antineoplastic agent, a neuroprotective agent, a hypoglycemic agent and a plant metabolite. It is a trimethoxyflavone and a monohydroxyflavone. It is functionally related to a scutellarein.
in vivo
Salvigenin (0-9.68 μg/mouse/day; i.p.; 4 or 12 days) shows antitumor and immunomodulatory effects on tumor bearing mice[2].
Animal Model: | MCF-7 cell bearing inbred female Balb/c mice, aged from six to eight weeks[2] |
Dosage: | 3.65, 5.85 and 9.68 μg/mouse/day for four days or 12 days |
Administration: | Intraperitoneal injection |
Result: | Showed a significant increase in DTH response in a dose-dependent manner. Significantly decreased the rate of tumor growth, increased lymphocyte proliferation index, increased the level of IFN-γ and decreased IL-4 production. Exhibited a significant decrease of the splenic CD4+CD25+Foxp3+ T lymphocytes. |
salvigenin Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29807 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32277 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10244 | 58 |
HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3461 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
View Lastest Price from salvigenin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-05-09 | Salvigenin
19103-54-9
|
US $65.00-263.00 / mg | 99.67% | 10g | TargetMol Chemicals Inc. | ||
|
2023-02-24 | Salvigenin
19103-54-9
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
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2020-02-21 | salvigenin
19103-54-9
|
US $8.00 / KG | 1g | >98% HPLC | kg---ton | Career Henan Chemical Co |
-
- Salvigenin
19103-54-9
- US $65.00-263.00 / mg
- 99.67%
- TargetMol Chemicals Inc.
-
- Salvigenin
19103-54-9
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- salvigenin
19103-54-9
- US $8.00 / KG
- >98% HPLC
- Career Henan Chemical Co