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ChemicalBook >> CAS DataBase List >>1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone

CAS No.
1125812-58-9
Chemical Name:
1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
Synonyms
1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one;afoxolaner-002;afoxolaner Impurity 6;1-[3-Chloro-5-trifluoromethylphenyl;2,2,2-trifluoro-3'-chloro-5'-trifluoromethylacetophenone;3'-Chloro-5'-trifluoroMethyl-2,2,2-trifluoroacetophenone;3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone;3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone;1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone;Ethanone, 1-[3-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoro-
CBNumber:
CB12514588
Molecular Formula:
C9H3ClF6O
Molecular Weight:
276.56
MDL Number:
MFCD19440960
MOL File:
1125812-58-9.mol
MSDS File:
SDS
Last updated:2023-06-09 13:57:52

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Properties

Boiling point 203℃
Density 1.512
Flash point 77℃
storage temp. 2-8°C

SAFETY

Risk and Safety Statements

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS146793 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone 95% 1125812-58-9 1g $120 2021-12-16 Buy
American Custom Chemicals Corporation HCH0361882 1-(3-CHLORO-5-(TRIFLUOROMETHYL)PHENYL)-2,2,2-TRIFLUOROETHANONE 95.00% 1125812-58-9 0.25G $243 2021-12-16 Buy
Ambeed A744788 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone 95+% 1125812-58-9 5g $255 2021-12-16 Buy
Crysdot CD12179721 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone 95+% 1125812-58-9 5g $750 2021-12-16 Buy
Chemenu CM274874 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone 95+% 1125812-58-9 500g $5520 2021-12-16 Buy
Product number Packaging Price Buy
AS146793 1g $120 Buy
HCH0361882 0.25G $243 Buy
A744788 5g $255 Buy
CD12179721 5g $750 Buy
CM274874 500g $5520 Buy

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Chemical Properties,Uses,Production

Uses

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

Synthesis_1125812-58-9
Cool the solution containing compound III (74.4g, 0.255mol containing compound III) to -100, and add 120g of sulfuric acid with a mass fraction of 92.5% to the above system while keeping the temperature below 0. After acidification, continue to react and keep for 1.5h, and then add 126.7g of 33% sodium nitrite aqueous solution (containing diazotizing reagent sodium nitrite 0.612mol) into the system uniformly within 2h, and keep the temperature at 0 The following reaction is carried out for 2 hours, and the system is heated to room temperature after full reaction, 111.1 g of 50% hypophosphorous acid and 0.67 g of cuprous oxide are added, and the reaction is stirred for 2 hours while keeping temperature. After the reaction is over, stand to separate the layers, and wash the organic layer with a 5% sodium bicarbonate aqueous solution, dry with anhydrous magnesium sulfate, and rectify to obtain a clear and transparent oily liquid 1-[3-chloro-5-(trifluoromethyl) (Yl)phenyl]-2,2,2-trifluoroethanone 66.9, content 99.5%, yield 87.2%.

383-63-1
928783-85-1
1125812-58-9
Synthesis of 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone from Ethyl trifluoroacetate and 3-Bromo-5-Chlorobenzotrifluoride

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Suppliers

Global( 146)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10032 58
ENBRIDGE PHARMTECH CO., LTD. 		+8613812269233 tinayang@enbridgepharm.com China 322 58
Masteam Bio-tech Co., Ltd. 		+86-15200345168 +86-15200345168 bruce.lei@masteam.com CHINA 151 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30239 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14426 58

View Lastest Price from 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone pictures 2023-11-01 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
1125812-58-9
 US $0.00-0.00 / kg 0.10000000149011612kg 98.0% min 1ton/month Hangzhou ICH Biofarm Co., Ltd
1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone pictures 2020-01-15 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
1125812-58-9
 US $1.00 / KG 1KG 99.0% 100kg Career Henan Chemical Co
1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone 3'-Chloro-5'-trifluoroMethyl-2,2,2-trifluoroacetophenone 2,2,2-trifluoro-3'-chloro-5'-trifluoromethylacetophenone 3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone Ethanone, 1-[3-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoro- 1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one (Afoxolaner intermediate） 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone ISO 9001：2015 REACH afoxolaner-002 1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one 1-[3-Chloro-5-trifluoromethylphenyl 3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone afoxolaner Impurity 6 1125812-58-9 1123812-58-9