4-METHYL-2-(5-PHENYL-1H-PYRAZOL-3-YL)PHENOL
- CAS No.
- 38214-71-0
- Chemical Name:
- 4-METHYL-2-(5-PHENYL-1H-PYRAZOL-3-YL)PHENOL
- Synonyms
- VRT-532;CFpot 532;VRT 532,VRT532;VRT-532 >=98% (HPLC);VRT-532, 10 mM in DMSO;4-METHYL-2-(5-PHENYL-1H-PYRAZOL-3-YL)PHENOL;PHENOL, 4-METHYL-2-(5-PHENYL-1H-PYRAZOL-3-YL)-
- CBNumber:
- CB12446623
- Molecular Formula:
- C16H14N2O
- Molecular Weight:
- 250.3
- MDL Number:
- MFCD01308792
- MOL File:
- 38214-71-0.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H318 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-41 |
| Safety Statements | 26-39 |
| WGK Germany | 2 |
4-METHYL-2-(5-PHENYL-1H-PYRAZOL-3-YL)PHENOL price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | V2390 | VRT-532 ≥98% (HPLC) | 38214-71-0 | 5mg | $140 | 2022-05-15 | Buy |
| American Custom Chemicals Corporation | CBL0000388 | VRT-532 95.00% | 38214-71-0 | 5MG | $504.91 | 2021-12-16 | Buy |
| Crysdot | CD11132131 | 4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol 95+% | 38214-71-0 | 1g | $528 | 2021-12-16 | Buy |
| Alichem | 38214710 | 4-Methyl-2-(5-phenyl-1h-pyrazol-3-yl)phenol | 38214-71-0 | 1g | $578.86 | 2021-12-16 | Buy |
4-METHYL-2-(5-PHENYL-1H-PYRAZOL-3-YL)PHENOL Chemical Properties,Uses,Production
Uses
VRT-532 (CFpot-532) is a potent is a potent CFTR modulator. VRT-532 enhances channel activity in G551D-CFTR and intrinsic ATPase activity of G551D-CFTR. VRT-532 has the potential for the research of cystic fibrosis[1][2].
References
[1] Pasyk S, et al. Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease. Biochem J. 2009 Feb 15;418(1):185-90. DOI:10.1042/BJ20081424
[2] Wang Y, et al. Correctors promote maturation of cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by binding to the protein. J Biol Chem. 2007 Nov 16;282(46):33247-33251. DOI:10.1074/jbc.C700175200
4-METHYL-2-(5-PHENYL-1H-PYRAZOL-3-YL)PHENOL Preparation Products And Raw materials
Raw materials
Preparation Products
4-METHYL-2-(5-PHENYL-1H-PYRAZOL-3-YL)PHENOL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32275 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38664 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988968278 | YN_research@163.com | China | 3000 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 4487 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1248 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24874 | 58 |
| Suzhou Zhixin Biotechnology Co., Ltd. | 0512-65118909 15162312715 | sales@szzxbio.com | China | 3000 | 58 |
