ChemicalBook >> CAS DataBase List >>4-Biphenylacetic acid
4-Biphenylacetic acid
- CAS No.
- 5728-52-9
- Chemical Name:
- 4-Biphenylacetic acid
- Synonyms
- FELBINAC;Napageln;BIPHENYL-4-ACETIC ACID;[1,1'-BIPHENYL]-4-ACETIC ACID;2-([1,1'-biphenyl]-4-yl)acetic acid;L-141;TraxaM;LY-61017;Seltouch;CI 83544
- CBNumber:
- CB0186272
- Molecular Formula:
- C14H12O2
- Molecular Weight:
- 212.24
- MDL Number:
- MFCD00004351
- MOL File:
- 5728-52-9.mol
- MSDS File:
- SDS
Last updated:2024-12-04 20:40:58
| Melting point | 159-160 °C (lit.) |
|---|---|
| Boiling point | 312.08°C (rough estimate) |
| Density | 1.1035 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble50mg/mL, clear, colorless to yellow |
| pka | 4.29±0.10(Predicted) |
| form | Powder |
| color | Beige |
| Water Solubility | 39.27mg/L(25 ºC) |
| Merck | 14,3316 |
| BRN | 1211592 |
| InChI | InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) |
| InChIKey | QRZAKQDHEVVFRX-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=CC=C2)=CC=C(CC(O)=O)C=C1 |
| CAS DataBase Reference | 5728-52-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 94WNJ5U8L7 |
| ATC code | M02AA08 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H331-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P301+P310-P302+P352-P304+P340+P311-P305+P351+P338 | |||||||||
| Hazard Codes | T,Xn | |||||||||
| Risk Statements | 23/25-36/37/38-25-36/37/38/63-20/21/22 | |||||||||
| Safety Statements | 26-36/37/39-45-37/39-28A-26/36/3745/60-20-36 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DU8229050 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29163900 | |||||||||
| Toxicity | LD50 orally in rats: 164 mg/kg (Sloboda, Osterberg) | |||||||||
| NFPA 704 |
|
4-Biphenylacetic acid price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 196487 | 4-Biphenylacetic acid 98% | 5728-52-9 | 5g | $60.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 196487 | 4-Biphenylacetic acid 98% | 5728-52-9 | 25g | $120 | 2023-01-07 | Buy |
| TCI Chemical | B1278 | 4-Biphenylacetic Acid >98.0%(HPLC)(T) | 5728-52-9 | 25g | $41 | 2024-03-01 | Buy |
| TCI Chemical | B1278 | 4-Biphenylacetic Acid >98.0%(HPLC)(T) | 5728-52-9 | 250g | $232 | 2024-03-01 | Buy |
| Alfa Aesar | A11749 | 4-Biphenylacetic acid, 98% | 5728-52-9 | 50g | $151 | 2023-06-20 | Buy |
4-Biphenylacetic acid Chemical Properties,Uses,Production
Description
Felbinac Is the active metabolite of the non-steroidal antiinflammatory agent, fenbufen. Applied topically as a gel to joints, it is useful in the symptomatic relief of articular inflammation and pain.
Chemical Properties
Off-white powder
Originator
Lederle (USA)
Uses
Anti-inflammatory, analgesic drug.
Uses
4-Biphenylacetic acid was used in the synthesis of gastrosparing non-steroidal antiinflammatory drug.
Definition
ChEBI: Biphenyl-4-ylacetic acid is a monocarboxylic acid in which one of the alpha-hydrogens is substituted by a biphenyl-4-yl group. An active metabolite of fenbufen, it is used as a topical medicine to treat muscle inflammation and arthritis. It has a role as a non-steroidal anti-inflammatory drug. It is a member of biphenyls and a monocarboxylic acid. It contains a biphenyl-4-yl group. It is functionally related to an acetic acid.
brand name
Dolinac (Wyeth-Ayerst); Flexfree(Wyeth-Ayerst); Napageln (Wyeth-Ayerst); Target (Wyeth-Ayerst); Traxam (Wyeth-Ayerst).
General Description
4-Biphenylacetic acid is a potential non-steroidal antiinflammatory agent and forms solid inclusion complex with β-cyclodextrin. 4-Biphenylacetic acid on interaction with quinolone antibacterial agents induces functional blockade of the γ-aminobutyric acid receptors.
Safety Profile
Poison by subcutaneous route.Moderately toxic by ingestion and intraperitoneal routes.An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits acrid smoke and fumes.
4-Biphenylacetic acid Preparation Products And Raw materials
Raw materials
Trimethoxyphenylsilane
[1,1'-BIPHENYL]-4-ACETIC ACID METHYL ESTER
1-Morpholin-4-yl-2-(4-phenylphenyl)ethanethione
carbon monoxide
2-([1,1'-biphenyl]-4-ylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1of3
Preparation Products
Global( 502)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Creating Bio-pharm co., ltd. | +8613586099526 | post@creatingbiopharm.com | China | 217 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12835 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 +86-16264648883 | niki@zlchemi.com | China | 2691 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18751 | 58 |
| Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 | sales@richfortunechem.com | China | 304 | 57 |
View Lastest Price from 4-Biphenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-20 | 4-Biphenylacetic acid
5728-52-9
|
US $10.00 / kg | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2024-12-13 | 4-Biphenylacetic acid
5728-52-9
|
US $0.00-0.00 / Kg/Drum | 1KG | 99%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-19 | Felbinac
5728-52-9
|
US $42.00 / mg | 99.55% | 10g | TargetMol Chemicals Inc. |
-
- 4-Biphenylacetic acid
5728-52-9
- US $10.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 4-Biphenylacetic acid
5728-52-9
- US $0.00-0.00 / Kg/Drum
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Felbinac
5728-52-9
- US $42.00 / mg
- 99.55%
- TargetMol Chemicals Inc.
5728-52-9(4-Biphenylacetic acid)Related Search:
4-BIPHENYLACETICABID
Biphenyl-4-acetic acid 97%
4-Biphenylacetic acid/Felbinac
4 -BIPHENYLACETIC ACID 99% BP GRADE
4-BIPHENYL ACETIC ACID 98.5%
4-BIPHENYLACETIC ACID(METHOXYMETHYL)-1,1''-BIPHENYL
4-Biphenylacetic acid ,99%
L-141
LJC-10141
LY-61017
4-Biphenylacetic aci
4-BIPHENYLYLACETIC ACID
P-BIPHENYLYLACETIC ACID
(Biphenyl-4-yl)acetic acid 97%
4-Biphenylacetic acid, 98% 10GR
NSC 16284
Seltouch
TraxaM
4-BIPHENYLYLACETIC ACID FOR SYNTHESIS
Biphenyl acetic acid(Felbinac)
Biphenyl-4-yl-acetic acid
CI 83544
4-PHENYLPHENYLACETIC ACID
4-CARBOXYMETHYLBIPHENYL
4-BIPHENYLACETIC ACID
4-Diphenylacetic Acid
P-BIPHENYLACETIC ACID
RARECHEM AL BO 0343
Felbinac(4-BiphenylaceticAcid)
4-Biphenylaceticacid,98+%
biphenyl acetic acide
4-biphenyl acetic acide
4-bisphenylacetic acid ( Felbinac）
Flurbiprofen-d3 (2-Fluoro-a-trideuteromethyl-[1,1&rsquo
Felbinac CRS
4-Biphenylacetic Acid >
4-Biphenylessigsaeure
2-([1,1'-biphenyl]-4-yl)acetic acid
BIPHENYL-4-ACETIC ACID
FELBINAC
[1,1'-BIPHENYL]-4-ACETIC ACID
Napageln
Talc 14807-96-6
Biphenyl monoacetic acid
Felbinac Crude
4-Biphenylacetic Methyl Ether
4-Biphenylacetic Acid, ≥ 97.0%
2-([1,1'-biphenyl]-4-yl)acetic acid
5728-52-9
57285-52-9
572-52-9
40728-52-9
C6H5C6H4CH2CO2H
C14H11O2
Organic Building Blocks
Building Blocks
C13 to C42+
Carbonyl Compounds