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Amphomycin

Amphomycin Struktur
1402-82-0
CAS-Nr.
1402-82-0
Bezeichnung:
Amphomycin
Englisch Name:
Amphomycin
Synonyma:
amfamycin;Nsc267431;Amphomycin
CBNumber:
CB9938498
Summenformel:
C58H91N13O20
Molgewicht:
1290.43
MOL-Datei:
1402-82-0.mol

Amphomycin Eigenschaften

alpha 
D25 +7.5° (c = 1 at pH 6)
Siedepunkt:
854.06°C (rough estimate)
Dichte
1.0985 (rough estimate)
Brechungsindex
1.6700 (estimate)
storage temp. 
Store at -20°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
solid
Farbe
Crystals

Sicherheit

Toxizit?t LD50 orl-mus: 500 mg/kg 85GDA2 4(1),317,80

Amphomycin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Amphomycin is a lipopeptide antibiotic produced by Streptomycetes and Actinoplanes, initially reported by researchers at Bristol-Myers in 1953 from Streptomyces canus. Amphomycin was marketed as a complex of closely related analogues in the 1950s and 1960s. Structure elucidation was not completed until 2000. Amphomycin is active against Gram positive bacteria, inhibiting peptidoglycan synthesis and blocking cell wall development. Amphomycin is closely related to a number of “l(fā)ost” antibiotics, aspartocin, crystallomycin, glumamycin, friulimicin, laspartocin, tsushimycin and zaomycin. Interest in amphomycin was re-awakened with the discovery of friulimicin activity against antibiotic resistant strains.

Sicherheitsprofil

Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion.Induces hemolysis. Active against gram-positive bacteria.Suggested as a topical agent for animal and plantinfections. When heated to decomposition it emits acridsmoke and

Amphomycin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Amphomycin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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