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Avermectin A1a, 5-O-Demethyl-22,23-dihydro-

Avermectin A1a, 5-O-demethyl-22,23-dihydro- Struktur
71827-03-7
CAS-Nr.
71827-03-7
Bezeichnung:
Avermectin A1a, 5-O-Demethyl-22,23-dihydro-
Englisch Name:
Avermectin A1a, 5-O-demethyl-22,23-dihydro-
Synonyma:
Ivermectin B1a;IvermectinH2B1a;Ivermectin B1a (>85%);Ivermectin Impurity 3;Dihydroavermectin B1a;22,23-dihydroavermectin B1a in Methanol;5-O-Demethyl-22,23-dihydroavermectin A1a;22,23-Dihydro-5-O-demethylavermectin A1a;Avermectin A1a, 5-O-demethyl-22,23-dihydro-;Ivermectin 2-epimer (Dihydro Avermectin B1a)
CBNumber:
CB9928288
Summenformel:
C48H74O14
Molgewicht:
875.09
MOL-Datei:
71827-03-7.mol

Avermectin A1a, 5-O-Demethyl-22,23-dihydro- Eigenschaften

Schmelzpunkt:
155-157°
Siedepunkt:
717.97°C (rough estimate)
Dichte
1.0683 (rough estimate)
Brechungsindex
1.6130 (estimate)
storage temp. 
Store at -20°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
solid
pka
12.42±0.70(Predicted)
Farbe
white
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P321 Besondere Behandlung
P330 Mund ausspülen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Avermectin A1a, 5-O-Demethyl-22,23-dihydro- Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ivermectin B1a is the main component (>80%) of the anthelmintic ivermectin, which also contains ivermectin B1b (<20%; ). It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening and very long-lasting hyperpolarization/depolarization of the neuron/muscle cell, thereby blocking further function (EC50 = 104 nM). Formulations containing ivermectin inhibit replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Vero/hSLAM cells.

Definition

ChEBI: A macrocyclic lactone that is avermectin B1a in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the major component of ivermectin.

Avermectin A1a, 5-O-Demethyl-22,23-dihydro- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4a-Hydroxy Ivermectin

Avermectin A1a, 5-O-Demethyl-22,23-dihydro- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 60)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501
 product@acmec-e.com China 33338 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658
 sales1@artkmedchem.com China 39004 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580
 cooperation@kean-chem.com China 40066 58
Moxin Chemicals 		+8617320513646
 mike@molcoo.com China 9498 58
QUALITY CONTROL SOLUTIONS LTD. 		0755-66853366; 13670046396
 ORDERS@QCSRM.COM China 24342 58
Guangzhou PI PI Biotech Inc 020-81716320 +86-13602409664
 Sales@pipitech.com China 3633 55
BioBioPha Co., Ltd. 0871-65217109 13211707573;
 y.liu@mail.biobiopha.com China 5653 65
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396
 sales@chem-strong.com China 18070 56

71827-03-7(Avermectin A1a, 5-O-Demethyl-22,23-dihydro-)Verwandte Suche:

  • 22,23-Dihydro-5-O-demethylavermectin A1a
  • 5-O-Demethyl-22,23-dihydroavermectin A1a
  • Dihydroavermectin B1a
  • Ivermectin B1a
  • IvermectinH2B1a
  • (2Ae,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17ar,20R,20ar,20bs)-20,20B-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-3',4',5',6,6',10,11,14,15,17,17A,20,20A,20B-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-o-(2,6-dideoxy-3-o-methyl-alpha-L-arabino-hexopyranosyl)-3-o-methyl-alpha-L-arabino-hexopyranoside
  • Avermectin A1a, 5-O-demethyl-22,23-dihydro-
  • Ivermectin Impurity 3
  • Ivermectin B1a (>85%)
  • Ivermectin B1a-D2Q: What is Ivermectin B1a-D2 Q: What is the CAS Number of Ivermectin B1a-D2
  • Avermectin,Ivermectin,B1a,COVID-19,Parasite,Inhibitor,SARS coronavirus,Ivermectin B1a,anti-parasite,inhibit,SARS-CoV
  • Ivermectin 2-epimer (Dihydro Avermectin B1a)
  • 22,23-dihydroavermectin B1a in Methanol
  • 71827-03-7
  • Organics
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