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D-Phenylalanin

D-Phenylalanine Struktur
673-06-3
CAS-Nr.
673-06-3
Bezeichnung:
D-Phenylalanin
Englisch Name:
D-Phenylalanine
Synonyma:
PHENYLALANINE;d-phe;H-D-PHE-OH;D-Phe-OH;(R)-PHENYLALANINE;(R)-2-amino-3-phenylpropanoic acid;NSC 25005;nci-c60195;Endorphenyl;D-Phenylalanin
CBNumber:
CB9773699
Summenformel:
C9H11NO2
Molgewicht:
165.19
MOL-Datei:
673-06-3.mol

D-Phenylalanin Eigenschaften

Schmelzpunkt:
273-276 °C(lit.)
Siedepunkt:
293.03°C (rough estimate)
alpha 
33.5 º (c=2, H2O)
Dichte
1.1603 (rough estimate)
Brechungsindex
34 ° (C=2, H2O)
storage temp. 
Store at RT.
L?slichkeit
Methanol (Slightly), Water (Slightly)
Aggregatzustand
Powder
pka
2.2(at 25℃)
Farbe
White to off-white
Wasserl?slichkeit
27 g/L (20 ºC)
Merck 
14,7271
BRN 
2804068
Stabilit?t:
Stable. Incompatible with strong oxidizing agents, acids, bases.
InChIKey
COLNVLDHVKWLRT-MRVPVSSYSA-N
LogP
0.235 (est)
CAS Datenbank
673-06-3(CAS DataBase Reference)
EPA chemische Informationen
D-Phenylalanine (673-06-3)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi,C
R-S?tze: 34
S-S?tze: 24/25-45-36/37/39-27-26
WGK Germany  3
RTECS-Nr. AY7533000
Hazard Note  Irritant
TSCA  Yes
HS Code  29224995
Toxizit?t TDLo orl-hmn: 500 mg/kg/5W-I:GIT JACTDZ 1(3),124,82
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

D-Phenylalanin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R34:Verursacht Ver?tzungen.

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getr?nkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

D-Phenylalanine, also known as D-alpha-Amino-beta-phenylpropionic acid, is a kind of non-proteinogenic amino acid. The biological function of D-phenylalanine remains unclear. However, it has certain anti-depressant, analgesic activities and pharmacological activity at niacin receptor II. The mechanism action of its analgesic activity seems to originate from its inhibition of enkephalin degradation by the carboxypeptidase A. Enkephalins are part of your body’s natural pain relief system. When they are broken down by enkephalinase, this contributes to the sensation of pain. D-Phenylalanine is specifically thought to be beneficial for reducing feelings of chronic pain. D-phenylalanine has been used with mixed results to treat chronic pain, including pain caused by rheumatoid arthritis. The primary use of D-phenylalanine as a health supplement is the relief of discomfort.

Chemische Eigenschaften

White crystalline powder

Verwenden

D-Phenylalanine, the stereoisomer of L-Phenylalanine (P319415) has been used in the synthesis of Schaeffer’s acid analogues as important structures in tuberculostatic design. They exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase.

Definition

ChEBI: D-phenylalanine is the D-enantiomer of phenylalanine. It is a phenylalanine and a D-alpha-amino acid. It is a conjugate base of a D-phenylalaninium. It is a conjugate acid of a D-phenylalaninate. It is an enantiomer of a L-phenylalanine. It is a tautomer of a D-phenylalanine zwitterion.

Allgemeine Beschreibung

D-phenylalanine appears as needles or prisms.

Air & Water Reaktionen

Water soluble. Aqueous solutions are weakly acidic.

Reaktivit?t anzeigen

D-alpha-Amino-beta-phenylpropionic acid may be light sensitive. D-alpha-Amino-beta-phenylpropionic acid reacts with strong oxidizing agents, acids and bases. . Act as weak acids in solution.

Brandgefahr

Flash point data for D-alpha-Amino-beta-phenylpropionic acid are not available, however D-alpha-Amino-beta-phenylpropionic acid is probably combustible.

Sicherheitsprofil

Mildly toxic by intraperitoneal route. Human systemic effects by ingestion: nausea, hypermotility, diarrhea. When heated to decomposition it emits toxic fumes of NOx.

Einzelnachweise

https://www.alfa.com/en/catalog/A10572/
https://en.wikipedia.org/wiki/Phenylalanine
Christianson, D. W., et al. "Binding of D-phenylalanine and D-tyrosine to carboxypeptidase A. " Journal of Biological Chemistry264.22(1989):12849-53.

D-Phenylalanin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


D-Phenylalanin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 726)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Weibang Biotechnology Co., Ltd
+8617732866630
bess@weibangbio.com China 18151 58
DONBOO AMINO ACID COMPANY
+8613063595538
donboo@donboo.com China 9363 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12835 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5857 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Firsky International Trade (Wuhan) Co., Ltd
+8615387054039
admin@firsky-cn.com China 427 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021
lisa@kingfinertech.com China 3010 58
Guangzhou Tengyue Chemical Co., Ltd.
+86-86-18148706580 +8618826483838
evan@tyvovo.com China 148 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58

673-06-3(D-Phenylalanin)Verwandte Suche:


  • D-PHENYLALANINE, >=98% (HPLC)
  • D-beta-Phenyl-alpha-aminopropionic acid
  • d-alpha-aminohydrocinnamic acid
  • D-ALPHA-AMINO-BETA-PHENYL-PROPIONIC ACID
  • D-2-AMINO-3-PHENYLPROPANOIC ACID
  • D(+)-PHENYLALANINE
  • D-PHENYLALANINE
  • RARECHEM AB PP 0687
  • (R)-2-AMINO-3-PHENYLPROPIONIC ACID
  • D-PHENYLALANINE, 99+% (98% EE/GLC)
  • D-Phenylalanine,>99%
  • D-α-Amino-β-phenylpropionic acid
  • Alanine, phenyl-, D- (8CI)
  • D-a-Amino-b-phenylpropionic acid
  • D-b-Phenylalanine
  • D-Phenylalanine (9CI)
  • NSC 25005
  • D-Phenylalanin
  • D-Phenglalanine,(R)-(+)-Phenglalanine
  • H-D-PHE-OH D-PHENYLALANINE
  • D-PHENYLALANINE ((R)-PHENYLALANINE)
  • (2R)-2-Amino-3-phenylpropanoic acid
  • (2R)-2-Amino-3-phenylpropionic acid
  • (R)-2-Benzylglycine
  • D-Phenylalanine≥ 99% (Assay)
  • D-PHENYLALANINE extrapure CHR
  • (R)-(+)-Phenylalanine, (R)-2-Amino-3-phenylpropionic acid, D-2-Amino-3-phenylpropanoic acid
  • nci-c60195
  • D-Phenylalanine,(R)-2-Amino-3-phenylpropionic acid
  • D-Phenylalanine Vetec(TM) reagent grade, >=98%
  • NATEGLINIDE INTERMEDIATES
  • D-Phenyl-d5-alanine-d3
  • Endorphenyl
  • D-2-Amino-3-phenylpropionic acid
  • D-3-Benzene-2-Amnopropanoic Acid
  • D-α-Aminohydrocinnamic acid
  • D-Phenylalanine, 99%, reagent grade
  • D-Phenylalanine>
  • D-Phenylalanine USP/EP/BP
  • D-Phenylalanine,0.98
  • dextro-phenyl alanine
  • D-phenylanaline
  • D-Phe-OH
  • d-phe
  • H-D-PHE-OH
  • (R)-PHENYLALANINE
  • PHENYLALANINE
  • (R)-2-amino-3-phenylpropanoic acid
  • (R)-Phenylalanine (Intermediate)
  • D-Phenylalanine (9CI, ACI)
  • (2S)-2-amino-3-phenylpropanoic acid (phenylalanine)
  • D-Phenylalanine(natural)
  • 673-06-3
  • 673-06-9
  • C6H5CH2CHNH2CO2H
  • Specialty Synthesis
  • Peptide Synthesis
  • Amino Acid Derivatives
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