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AMITRIPTYLINE METABOLITE (+/-)-

AMITRIPTYLINE METABOLITE (+/-)- Struktur
64520-05-4
CAS-Nr.
64520-05-4
Englisch Name:
AMITRIPTYLINE METABOLITE (+/-)-
Synonyma:
10-Hydroxy (E)-Amitriptyline;AMITRIPTYLINE METABOLITE (+/-)-;AMITRIPTYLINE METABOLITE (+-)-(E)-10-HYD ROXYLA;Amitriptyline metabolite, (±)-E-10-hydroxylated-;(E)-5-(3-(Dimethylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol;5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)-;(11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol
CBNumber:
CB9496952
Summenformel:
C20H23NO
Molgewicht:
293.4
MOL-Datei:
64520-05-4.mol

AMITRIPTYLINE METABOLITE (+/-)- Eigenschaften

Schmelzpunkt:
97-99 °C
Siedepunkt:
453.3±45.0 °C(Predicted)
Dichte
1.151±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
0.1 M HCl: soluble
Aggregatzustand
solid
pka
13.89±0.20(Predicted)
Farbe
white
Stabilit?t:
Hygroscopic
EPA chemische Informationen
5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)- (64520-05-4)

Sicherheit

S-S?tze: 22-24/25
WGK Germany  3

AMITRIPTYLINE METABOLITE (+/-)- Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

(5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

Biochem/physiol Actions

Metabolite of amitriptyline, tricyclic antidepressant; chromatographic standard.

AMITRIPTYLINE METABOLITE (+/-)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

AMITRIPTYLINE METABOLITE (+/-)- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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64520-05-4()Verwandte Suche:

  • AMITRIPTYLINE METABOLITE (+/-)-
  • AMITRIPTYLINE METABOLITE (+-)-(E)-10-HYD ROXYLA
  • (11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol
  • 5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)-
  • 10-Hydroxy (E)-Amitriptyline
  • Amitriptyline metabolite, (±)-E-10-hydroxylated-
  • (E)-5-(3-(Dimethylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol
  • 64520-05-4
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