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Cyclosporin A-Derivative 1 Free base

Cyclosporin A-Derivative 1 Free base Struktur
286852-20-8
CAS-Nr.
286852-20-8
Englisch Name:
Cyclosporin A-Derivative 1 Free base
Synonyma:
Cyclosporin A-Derivative 1 Free base;N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-;Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester
CBNumber:
CB94844681
Summenformel:
C65H117N11O14
Molgewicht:
1276.69
MOL-Datei:
286852-20-8.mol

Cyclosporin A-Derivative 1 Free base Eigenschaften

Siedepunkt:
1225.9±65.0 °C(Predicted)
Dichte
1.093±0.06 g/cm3(Predicted)
L?slichkeit
DCM, Methanol
Aggregatzustand
Solid
pka
13.07±0.46(Predicted)
Farbe
Off-White

Sicherheit

Cyclosporin A-Derivative 1 Free base Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.

Cyclosporin A-Derivative 1 Free base Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cyclosporin A-Derivative 1 Free base Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • Cyclosporin A-Derivative 1 Free base
  • N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-
  • Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester
  • 286852-20-8
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