Dolutegravir 4-Desfluoro Impurity
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- CAS-Nr.
- 1863916-87-3
- Englisch Name:
- Dolutegravir 4-Desfluoro Impurity
- Synonyma:
- Dotiravir Impurity 2;Dotiravir Impurity 8;2-Fluoro Dolutegravir;4-Defluoro Dolutegravir;Dolutegravir Impurity 49;Dolutegravir Impurity 46;Doultegravir 2-F Impurity C;Dolutegravir 2-Fluoro Impurity;Dolutegravir 4-Desfluoro Impurity;Dolutegravir Impurity C (4-Defluoro Dolutegravir)
- CBNumber:
- CB94796146
- Summenformel:
- C20H20FN3O5
- Molgewicht:
- 401.39
- MOL-Datei:
- 1863916-87-3.mol
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Dolutegravir 4-Desfluoro Impurity Eigenschaften
- Siedepunkt:
- 671.6±55.0 °C(Predicted)
- Dichte
- 1.49±0.1 g/cm3(Predicted)
- pka
- 4.50±1.00(Predicted)
Sicherheit
Dolutegravir 4-Desfluoro Impurity Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
4-Defluro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dolutegravir 4-Desfluoro Impurity Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Dolutegravir 4-Desfluoro Impurity Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 35)Lieferanten
- Dolutegravir impurity 1/4-Defluoro Dolutegravir/(4R,12aS)-N-(2-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- (4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- 4-Defluoro Dolutegravir
- 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
- Doultegravir 2-F Impurity C
- Dolutegravir Impurity C (4-Defluoro Dolutegravir)
- Dolutegravir Impurity 46
- Dolutegravir Impurity 49
- 2-Fluoro Dolutegravir
- Dolutegravir 4-Desfluoro Impurity
- Dotiravir Impurity 2
- Dotiravir Impurity 8
- Dolutegravir 2-Fluoro Impurity
- 1863916-87-3
