SD 2590 HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
SD 2590 is an inhibitor of matrix metalloproteinase-2 (MMP-2), -3, -8, -9, and -13 (IC
50s = <0.1, 28.7, 1.7, 0.18, and <0.1 nM, respectively). It is selective for these MMPs over MMP-1 and MMP-7 (IC
50s = >10,000 and 7,000 nM, respectively). SD 2590 (10 mg/kg per day) inhibits dilation of the left ventricle in rats following myocardial infarction (MI) compared to MI vehicle control animals.
Verwenden
SD 2590 Hydrochloride is an orally active MMP inhibitor with efficacy in cancer, arthritis and cardiovascular disease.
SD 2590 HYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte