Doxylaminhydrogensuccinat
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- CAS-Nr.
- 562-10-7
- Bezeichnung:
- Doxylaminhydrogensuccinat
- Englisch Name:
- Doxylamine succinate
- Synonyma:
- unisom;decapryn;hoggarn;gittalun;sedaplus;alsadorm;mereprine;DoxylaMineSuccinat;Decapryn succinate;DOXYLAMINE SUCCINATE
- CBNumber:
- CB9416701
- Summenformel:
- C21H28N2O5
- Molgewicht:
- 388.46
- MOL-Datei:
- 562-10-7.mol
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Doxylaminhydrogensuccinat Eigenschaften
- Schmelzpunkt:
- 95-98?C
- Flammpunkt:
- 9℃
- storage temp.
- 2-8°C
- L?slichkeit
- Very soluble in water, freely soluble in ethanol (96 per cent).
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Stabilit?t:
- Stable, but may be light sensitive. Incompatible with strong oxidizing agents, acids, bases.
- InChIKey
- KBAUFVUYFNWQFM-UHFFFAOYSA-N
- LogP
- 2.519 (est)
- CAS Datenbank
- 562-10-7(CAS DataBase Reference)
- IARC
- 3 (Vol. 79) 2001
- EPA chemische Informationen
- Doxylamine succinate (1:1) (562-10-7)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn,T,F |
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| R-S?tze: |
22-36/37/38-20/21/22-39/23/24/25-23/24/25-11 |
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| S-S?tze: |
26-36/37-45-16-7 |
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| RIDADR |
UN1230 - class 3 - PG 2 - Methanol, solution |
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| WGK Germany |
2 |
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| RTECS-Nr. |
US9275000 |
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| HS Code |
2933399090 |
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| Toxizit?t |
LD50 in mice, rabbits (mg/kg): 470, 250 orally; 62, 49 i.v.; in mice, male rats, female rats (mg/kg): 460, 440, 445 s.c. (Brown, Werner) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
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Doxylaminhydrogensuccinat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
white to light cream powder
Verwenden
Doxylamine succinate salt has been used as a therapeutic drug to check developmental toxicity.
Allgemeine Beschreibung
The acid succinate salt (bisuccinate)of doxylamine, 2-[ -[2-(dimethylamino)ethoxy]- -methylbenzyl]pyridine bisuccinate (Decapryn Succinate), isa white to creamy-white powder with a characteristic odor.It is soluble in water (1:1), alcohol (1:2), and chloroform(1:2). A 1% solution has a pH of about 5.Doxylamine succinate is comparable in potency todiphenhydramine. It is indicated for the relief of seasonalrhinitis symptoms, but is also used as a nighttime sedative.Concurrent use of alcohol and other CNS depressantsshould be avoided.
Air & Water Reaktionen
Water soluble.
Health Hazard
SYMPTOMS: Symptoms of exposure to Doxylamine succinate may include drowsiness, excitability, nervousness, dizziness and sleeplessness.
Brandgefahr
Flash point data for Doxylamine succinate are not available. Doxylamine succinate is probably combustible.
Doxylaminhydrogensuccinat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Doxylaminhydrogensuccinat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 341)Lieferanten
562-10-7(Doxylaminhydrogensuccinat)Verwandte Suche:
- Doxylaminhydrogensuccinat
- N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine succinate
- DOXLAMINE SUCCINATE USP
- [(3-carboxypropanoyl)oxy]diMethyl{2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethyl}aMinyl
- Butanedioic acid, compd. with N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1)
- Doxylamine for system suitability
- Doxylamine succinate solution
- doxylaminesuccinate(1:1)
- gittalun
- hoggarn
- mereprine
- phenyl2-pyridylmethyl-beta-n,n-dimethylaminoethylethersuccinate
- sedaplus
- N,N-DIMETHYL-2-[1-PHENYL-1-(2-PYRIDINYL)ETHOXY]ETHENAMINE SUCCINATE
- LABOTEST-BB LT00244822
- DOXYLAMINE SUCCINATE
- DOXYLAMINE SUCCINATE SALT
- 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-pyridinsuccinate(1
- 2-(alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl)pyridinesuccinate
- 2-dimethylaminoethoxyphenylmethyl-2-picolinesuccinate
- alsadorm
- decarpynsuccinate(1:1)
- dimethylaminoethoxy-methyl-benzyl-pyridinesuccinate
- DoxylaMineSuccinat
- Doxylamine Succinate (300 mg)
- Decapryn succinate
- DOXYLAMINESUCCINATE,USP
- N,N-dimethyl-2-(1-phenyl-1-pyridin-2-yl-ethoxy)ethanamine
- Doxylamine hydrogen succinate CRS
- Doxylamine for system suitability CRS
- Doxylaminesuccinatesal
- N,N-Dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine Succinate
- Doxylamine succinate USP/EP/BP
- doxl amine succinate
- Doxylamine succinateQ: What is
Doxylamine succinate Q: What is the CAS Number of
Doxylamine succinate Q: What is the storage condition of
Doxylamine succinate Q: What are the applications of
Doxylamine succinate
- Doxylamine Succinate (1227006)
- unisom
- decapryn
- Docylamine succinate
- N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine (Doxylamine succinate)
- Butanedioic acid, compd. withN,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1)OTHER CA INDEX NAMES:Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-,butanedioate (1:1)
- Doxylamine succinate in methanol
- 562-10-7
- C17H22N2OC4H6O4
- API
- DECAPRYN
- Other APIs
- Antagonists
- Histaminergics
- Neurotransmitters
- Amines
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Neurochemicals
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