2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE
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- CAS-Nr.
- 19752-61-5
- Englisch Name:
- 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE
- Synonyma:
- IFLAB-BB F1371-0151;2,4-DI-T-BUTOXY-5-BROMO-PYRIMIDINE;Oxirane, 2-[14-(phenylMethoxy)ethyl]-;5-broMo-2,4-bis(tert-butoxy)pyriMidine;2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE;5-BROMO-2,4-DI-(TERT-BUTOXY)PYRIMIDINE;5-Bromo-2,4-di-(tert-butoxy)pyrimidine 95%;5-BroMo-2,4-bis(1,1-diMethylethoxy)pyriMidine;Pyrimidine, 5-bromo-2,4-bis(1,1-dimethylethoxy)-;Benzaldehyde,4-(4,6-dichloro-1,3,5-triazin-4-yl)-
- CBNumber:
- CB9323582
- Summenformel:
- C12H19BrN2O2
- Molgewicht:
- 303.2
- MOL-Datei:
- 19752-61-5.mol
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2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Eigenschaften
- Schmelzpunkt:
- 58-61°C
- Siedepunkt:
- 352.0±45.0 °C(Predicted)
- Dichte
- 1.267±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- DCM, Ethyl Acetate, Methanol
- pka
- 1.73±0.29(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White
2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
5-Bromo-2,4-bis(1,1-dimethylethoxy)pyrimidine is an intermediate in the synthesis of β-Pseudouridine (O839607), an isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA.
Synthese
5-Bromo-2,4-dichloropyrimidine (10.0 mmol, 2.28 g) is dissolved in dry THF (50 mL). Then a solution of sodium tert-butoxide (25.0 mmol, 2.40 g) in THF (100 mL) is added dropwise at rt and the reaction mixture stirred for 5 h. The reaction is quenched with water (50 mL) and extracted with EtOAc (3 x 50 mL). Purification by flash chromatography yielded the desired product 5 as colorless solid (2.79 g, 92%). 5-Bromo-2,4-di-tert-butoxypyrimidine 5 ,Yield 2.79 g, 92%.
2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 88)Lieferanten
19752-61-5()Verwandte Suche:
- IFLAB-BB F1371-0151
- 5-BROMO-2,4-DI-(TERT-BUTOXY)PYRIMIDINE
- 2,4-DI-T-BUTOXY-5-BROMO-PYRIMIDINE
- 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE
- 5-broMo-2,4-bis(tert-butoxy)pyriMidine
- 5-BroMo-2,4-bis(1,1-diMethylethoxy)pyriMidine
- 5-bromo-2,4-bis[(2-methylpropan-2-yl)oxy]pyrimidine
- 5-Bromo-2,4-di-(tert-butoxy)pyrimidine 95%
- Pyrimidine, 5-bromo-2,4-bis(1,1-dimethylethoxy)-
- 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE ISO 9001：2015 REACH
- Benzaldehyde,4-(4,6-dichloro-1,3,5-triazin-4-yl)-
- Oxirane, 2-[14-(phenylMethoxy)ethyl]-
- 19752-61-5
- Pyrimidines
