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Piromelatine

Piromelatine Struktur
946846-83-9
CAS-Nr.
946846-83-9
Englisch Name:
Piromelatine
Synonyma:
NEU-P11;NEU-P-11;NEU-P 11;Piromelatine;Piromelatine (Neu-P11);Piromelatine 946846-83-9;N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxopyran-2-carboxamide;4H-Pyran-2-carboxamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxo-
CBNumber:
CB93151928
Summenformel:
C17H16N2O4
Molgewicht:
312.32
MOL-Datei:
946846-83-9.mol

Piromelatine Eigenschaften

Aggregatzustand
Solid
Farbe
Light yellow to yellow

Sicherheit

Piromelatine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Piromelatine is a novel investigational agent that has agonist activity at MT1 and MT2 along with agonism at 5-HT1A/1D receptors. A phase II randomized clinical trial (N 1/4 120) in primary insomnia resulted in significant improvement in insomnia symptoms.

Clinical claims and research

Piromelatine known as Neu-P11 is a newer melatonin receptor agonist underdevelopmental stage. It acts on MT1, MT2, and also 5-HT1A/5- HT1D receptors. It has demonstrated improvement in the sleep cycle of primary insomnia patients and reducing sleep disturbances in Phase II clinical trial. It was found to have efficacy in maintaining deeper sleep, less arousal, and also preserving REM sleep pattern. In the clinical trial, piromelatine was well tolerated with no adverse effects on psychomotor performance the following day (She et al., 2014).

Piromelatine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Piromelatine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 15)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
Shanghai Boyle Chemical Co., Ltd.
sales@boylechem.com China 2922 55
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
klq@cw-bio.com China 4966 55
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
sales@rechemscience.com China 2988 58
Shanghai Biopharmaleader Co., Ltd. +86 18721201413
sales@biopharmaleader.com China 1720 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761
486064515@qq.com China 4315 58
Kaifeng Mingren Pharmaceutical Co.,LTD 0371-65741762
sales@hasunny.com China 2380 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24644 58
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602
2853979810@qq.com China 9989 58

  • Piromelatine
  • Piromelatine 946846-83-9
  • N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxopyran-2-carboxamide
  • 4H-Pyran-2-carboxamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxo-
  • NEU-P 11
  • NEU-P11
  • NEU-P-11
  • Piromelatine (Neu-P11)
  • 946846-83-9
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