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Aprepitant Impurity 6

Aprepitant Impurity 6 Struktur
170902-81-5
CAS-Nr.
170902-81-5
Englisch Name:
Aprepitant Impurity 6
Synonyma:
1S, 2R, 3S-Aripitan;Aprepitant Impurity 5(S,R,S-Isomer);Fosaprepitant Dimeglumine Impurity A;Arepitam impurity isomers (1S, 2R, 3S);Fosaprepitant Dimeglumine EP Impurity A;Aprepitant impurity 9/(1S,2R,3S)-Aprepitant;[1(S)-Phenylethoxy]-Aprepitant/ Aprepitant S,R,S-Isomer;5-([(2R,3S)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
CBNumber:
CB93146511
Summenformel:
C23H21F7N4O3
Molgewicht:
534.43
MOL-Datei:
170902-81-5.mol

Aprepitant Impurity 6 Eigenschaften

Dichte
1.51±0.1 g/cm3(Predicted)
pka
8.06±0.20(Predicted)

Sicherheit

Aprepitant Impurity 6 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

[1(S)-Phenylethoxy]-Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 6 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Aprepitant Impurity 6 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 41)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Standardpharm Co. Ltd. 		86-714-3992388
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CR Corporation Limited 		+8613062833949
 fred.wen@crcorporation.cn China 8647 58
sgtlifesciences pvt ltd 		+8617013299288
 dj@sgtlifesciences.com China 12373 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522
 overseasales@yongstandards.com China 11922 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+8618627948422
 sale@hdimpurity.com China 3389 58
Guangzhou CATO Research Chemicals Inc. 		+86-020-81960175-617 +8615602392859
 Intermediate@cato-chem.com China 8322 58
Moxin Chemicals 		+8617320513646
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BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 14055 65
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412
 3001272453@qq.com China 5047 50
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396
 sales@chem-strong.com China 18070 56

170902-81-5()Verwandte Suche:

  • Fosaprepitant Dimeglumine Impurity A
  • Aprepitant Impurity 5(S,R,S-Isomer)
  • Aprepitant impurity 9/(1S,2R,3S)-Aprepitant
  • 1S, 2R, 3S-Aripitan
  • Arepitam impurity isomers (1S, 2R, 3S)
  • 5-([(2R,3S)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one
  • 3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
  • Fosaprepitant Dimeglumine EP Impurity A
  • 5-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
  • [1(S)-Phenylethoxy]-Aprepitant/ Aprepitant S,R,S-Isomer
  • 170902-81-5
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