Tumor suppressor candidate 3 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-TUSC3 antibody has been used in immunohistochemistry, immunoblotting and co-immunoprecipitation.
Allgemeine Beschreibung
Tumor suppressor candidate 3 (TUSC3) codes for a subunit of the endoplasmic reticulum-bound?oligosaccharyltransferase?complex. It is a 348 amino acid protein, that has 11 exons spanning ～224 Kbp of the genomic DNA. TUSC3 has five potential?transmembrane domains and is located on human chromosome 8p22.
Biochem/physiol Actions
Tumor suppressor candidate 3 (TUSC3) is a tumor suppressor gene, that is responsible for autosomal recessive mental retardation. It participates in catalyzing the transfer of a 14-sugar?oligosaccharide?from?dolichol to nascent protein. Absence of TUSC3 is associated with lymph node metastasis in larynx and pharynx squamous cell carcinomas.
Tumor suppressor candidate 3 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
