KIAA1369 Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Eukaryotic translation initiation factor 2-α kinase 1 (EIF2AK1) or HRI is a kinase that can be inactivated by hemin. The gene encoding this protein is localized on human chromosome 7p22.1.

Biochem/physiol Actions

Eukaryotic translation initiation factor 2-α kinase 1 (EIF2AK1) modulates protein synthesis. It acts at the level of translation initiation to downregulate protein synthesis in response to stress. The protein is activated by heme deficiency and other stimuli and is a major protein kinase that phosphorylates EIF2-α. EIF2AK1 is downregulated in the majority of ovarian cancers compared with normal ovarian tissues. It functions in iron homeostasis and may play a role in hemolytic and inflammatory anemia.

KIAA1369 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

KIAA1369 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Merck KGaA	(+86) 21 2033 8288	sigmaname@qq.com	CHINA	292394	58

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• ANTI-HRI(N-TERMINAL) antibody produced in rabbit
• EIF2AK1
• Eukaryotic translation initiation factor 2-alpha kinase 1
• Heme-controlled repressor
• HRI
• KIAA1369
• EIF2AK3
• HsPEK
• Pancreatic eIF2-alpha kinase
• Anti-EIF2AK1, C-Terminal antibody produced in rabbit
• Eukaryotic translation initiation factor 2-α kinase 1
• Heme-regulated eukaryotic initiation factor eIF-2-α kinase
• Heme-regulated inhibitor
• Hemin-sensitive initiation factor 2-α kinase
• EIF2AK1 (HRI), active, GST tagged human