MSP1E3D1
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- CAS-Nr.
- Englisch Name:
- MSP1E3D1
- Synonyma:
- MSP1E3D1;Membrane Scaffold Protein 1E3D1
- CBNumber:
- CB92886748
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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MSP1E3D1 Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- lyophilized powder
- Biologische Quelle
- Streptomyces kanamyceticus
- Wasserl?slichkeit
- water: soluble
- ε(Extinktionskoeffizient)
- 26,600M-1cm-1 at 280nm (His-tag-cleaved dissolved in 20 mM Tris pH 7.40.1M NaCl0.5mM EDTA and 0.01%NaN3)(lit.)
29,400M-1cm-1 at 280nm (uncleaved His-tagged dissolved in 20 mM Tris pH 7.40.1M NaCl0.5mM EDTA and 0.01%NaN3)(lit.)
MSP1E3D1 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
The nanodisc system has been employed to incorporate a wide variety of proteins including GPCRs, P450s, bacteriorhodopsin, coagulation factors, cholera toxin, TAR receptor and aromatase.
Allgemeine Beschreibung
The nanodisc concept is derived from high density lipoprotein (HDL) particles and their primary protein component, apolipoprotein. The nanodisc is a non-covalent structure of phospholipid bilayer and membrane scaffold protein (MSP), a genetically engineered protein, which mimics the function of Apolipoprotein A-1 (ApoA-1). A soluble nanodisc assembles as the phospholipid forms a bilayer, which is encircled by two amphipathic MSP molecules covering the hydrophobic alkyl chains of the bilayer. The length of the MSP controls the size of the nanodisc structure. MSP1E3D1 yields nanodiscs of ~12.9 nm. The thickness of a nanodisc is dependent on the type of phospholipid incorporated (typically 4.6?5.6 nm).
Biochem/physiol Actions
Generates Nanodiscs ~12.9 nm in diameter
MSP1E3D1 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
MSP1E3D1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 3)Lieferanten
- Membrane Scaffold Protein 1E3D1
- MSP1E3D1
