Tie-2 Inhibitor 7 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Tie2 Inhibitor 7 blocks Tie2 kinase activity with a K
i value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC
50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.
Tie-2 Inhibitor 7 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte