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Tie-2 Inhibitor 7

Tie-2 Inhibitor 7 Struktur
1020412-97-8
CAS-Nr.
1020412-97-8
Englisch Name:
Tie-2 Inhibitor 7
Synonyma:
Tie2 inhibitor;Tie inhibitor 7;Tie-2 Inhibitor 7;TIE2 INHIBITOR;TIE INHIBITOR 7;Tie2 Inhibitor 7,Tie-2 Inhibitor 7;(S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinic acid;3-Pyridinecarboxylic acid, 5-[4-[[[2-[[(1S)-1-cyclohexylethyl]amino]-2-oxoethyl][(4-methylphenoxy)carbonyl]amino]methyl]phenyl]-
CBNumber:
CB92684135
Summenformel:
C31H35N3O5
Molgewicht:
529.63
MOL-Datei:
1020412-97-8.mol

Tie-2 Inhibitor 7 Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
DMF: 14 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml; Ethanol: 1 mg/ml
Aggregatzustand
A crystalline solid

Sicherheit

Tie-2 Inhibitor 7 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 μM.. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 μM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model of Matrigel-induced choroidal neovascularization.

Tie-2 Inhibitor 7 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tie-2 Inhibitor 7 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 19)Lieferanten
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ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
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Alfa Chemistry

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ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054
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Aladdin Scientific
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Chembest Research Laboratories Limited +86-21-20908456
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BOC Sciences 16314854226
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
lucy@atkchemical.com China 9952 58

  • Tie-2 Inhibitor 7
  • Tie inhibitor 7
  • Tie2 inhibitor
  • TIE2 INHIBITOR;TIE INHIBITOR 7
  • (S)-5-(4-(((2-((1-Cyclohexylethyl)amino)-2-oxoethyl)((p-tolyloxy)carbonyl)amino)methyl)phenyl)nicotinic acid
  • 3-Pyridinecarboxylic acid, 5-[4-[[[2-[[(1S)-1-cyclohexylethyl]amino]-2-oxoethyl][(4-methylphenoxy)carbonyl]amino]methyl]phenyl]-
  • Tie2 Inhibitor 7,Tie-2 Inhibitor 7
  • 1020412-97-8
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