2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione
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- CAS-Nr.
- 332382-54-4
- Englisch Name:
- 2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione
- Synonyma:
- ML-SA1;STK095286;EU-0040486;MLS000526272;BAS 01520422;SMR000116746;Oprea1_593964;Oprea1_383174;CBMicro_009667;ChemDiv1_023217
- CBNumber:
- CB92555129
- Summenformel:
- C22H22N2O3
- Molgewicht:
- 362.42
- MOL-Datei:
- 332382-54-4.mol
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2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione Eigenschaften
- Siedepunkt:
- 546.7±43.0 °C(Predicted)
- Dichte
- 1.226±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: soluble5mg/mL, clear (warmed)
- pka
- 1.16±0.60(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
ML-SA1 has been used as a transient receptor potential cation channel mucolipin 1 (TRPML1/ML1) agonist.
Biochem/physiol Actions
ML-SA1 is a potent and selective cell permeable agonist of lysosomal mucolipin transient receptor potential channels (TRPML) 1, 2, 3 that significantly increases [Ca2+]cyt in HEK293 cells stably- or transiently-expressing mutant TRPML1 channels ML1-4A.
2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 90)Lieferanten
332382-54-4()Verwandte Suche:
- 2-[2-oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1-yl)ethyl]isoindole-1,3-dione
- 2-[2-oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1-yl)ethyl]isoindoline-1,3-dione
- BAS 01520422
- BIM-0009825.P001
- CBMicro_009667
- ChemDiv1_023217
- EU-0040486
- MLS000526272
- Oprea1_383174
- Oprea1_593964
- SMR000116746
- STK095286
- TRPML Agonist, ML-SA1
- 2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione
- 1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]-1,2,3,4-tetrahydro-2,2,4-trimethyl-quinoline
- 2-(2-Oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl)isoindoline-1,3-dione
- ML-SA1
- Mucolipin Synthetic Agonist 1
- 2-[2-keto-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1-yl)ethyl]isoindoline-1,3-quinone
- 2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydro-2H-quinolin-1-yl)-ethyl]-isoindole-1,3-dione
- TRPML Agonist, ML-SA1 - CAS 332382-54-4 - Calbiochem
- 2-[2-(3,4-Dihydro-2,2,4-trimethyl-1(2H)-quinolinyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione
- 1H-Isoindole-1,3(2H)-dione, 2-[2-(3,4-dihydro-2,2,4-trimethyl-1(2H)-quinolinyl)-2-oxoethyl]-
- ML-SA1,lysosomal,ML SA1,Inhibitor,inhibit,protease,Transient receptor potential channels,autophagy,broad-spectrum,selective,acidification,Zika,MLSA1,ML-SA-1,antiviral,TRP Channel,virus,Dengue
- 332382-54-4