ANTI-CALCIUM CHANNEL (ALPHA1B SUBUNIT) (N-TYPE OF VOLTAGE-GATED CA2+ CHANNEL) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-Calcium Channel (α1B Subunit) (N-type of Voltage-gated Ca
2+ Channel) antibody produced in rabbit has been used in immunofluorescence analysis.
Allgemeine Beschreibung
The calcium channel, voltage-dependent, N type, α1B subunit (CACNA1B) or Cav2.2 gene consists of 47 exons and 46 introns, spanning 244kb. The gene is mapped to human chromosome 9q34. The encoded protein is a member of the voltage-gated calcium channel family.
Biochem/physiol Actions
Calcium channel, voltage-dependent, N type, α1B subunit (CACNA1B) plays a vital role in regulation of trafficking and biophysical properties of voltage-gated calcium channels. Members of voltage-gated calcium channel family act as key transducers of cell surface membrane potential changes to local intracellular calcium transients that initiate various physiological events. The N-type voltage-gated calcium channels (VGCCs) expressed mainly in the neurons, facilitate neurotransmitter release at the sympathetic nerve terminals. CACNA1B is expressed on presynaptic nerve terminals of nociceptors control neurotransmitter release.
ANTI-CALCIUM CHANNEL (ALPHA1B SUBUNIT) (N-TYPE OF VOLTAGE-GATED CA2+ CHANNEL) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte