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Ro 3306

Ro 3306 Struktur
872573-93-8
CAS-Nr.
872573-93-8
Englisch Name:
Ro 3306
Synonyma:
CS-770;Ro 3306;RO3306;RO 3306;Ro 3306 USP/EP/BP;5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone;(5Z)-5-Quinolin-6-ylmethylene-2-[(thiophen-2-ylmethyl)-amino]-thiazol-4-one;(Z)-5-(quinolin-6-ylmethylene)-2-(thiophen-2-ylmethylamino)thiazol-4(5H)-one;4(5H)-Thiazolone, 5-(6-quinolinylmethylene)-2-[(2-thienylmethyl)amino]-, (5Z)-;(5Z)-5-(quinolin-6-ylmethylidene)-2-(thiophen-2-ylmethylamino)-1,3-thiazol-4-one;2-[[(Thiophen-2-yl)methyl]amino]-5-[1-(quinolin-6-yl)meth-(Z)-ylidene]thiazol-4-one
CBNumber:
CB92535693
Summenformel:
C18H13N3OS2
Molgewicht:
351.45
MOL-Datei:
872573-93-8.mol

Ro 3306 Eigenschaften

Siedepunkt:
569.1±60.0 °C(Predicted)
Dichte
1.41
storage temp. 
2-8°C
L?slichkeit
DMSO: soluble5mg/mL, clear
pka
3.99±0.10(Predicted)
Aggregatzustand
powder
Farbe
white to light brown
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Sicherheit

WGK Germany  3

Ro 3306 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

RO-3306 is an ATP-competitive and selective CDK1 inhibitor used against a diverse panel of human kinases. Used in the treatment of malignant tumors in conjunction with PARP inhibitors.

Biochem/physiol Actions

RO-3306 is a selective ATP-competitive inhibitor of CDK1. It inhibites CDK1 cyclin B1 activity with Ki of 35 nM, nearly 10-fold selectivity relative to CDK2/cyclin E and over 50-fold relative to CDK4/cyclin D. RO-3306 has been used to cause cell cycle arrest at the G2/M boundary.

Ro 3306 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Ro 3306 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 113)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32957 60
Hubei xin bonus chemical co. LTD 		86-13657291602
linda@hubeijusheng.com CHINA 22963 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29811 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289
 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 22784 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3135 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58

872573-93-8()Verwandte Suche:

  • Ro 3306
  • 2-[[(Thiophen-2-yl)methyl]amino]-5-[1-(quinolin-6-yl)meth-(Z)-ylidene]thiazol-4-one
  • (Z)-5-(quinolin-6-ylmethylene)-2-(thiophen-2-ylmethylamino)thiazol-4(5H)-one
  • (5Z)-5-Quinolin-6-ylmethylene-2-[(thiophen-2-ylmethyl)-amino]-thiazol-4-one
  • 5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone
  • RO3306;RO 3306
  • 4(5H)-Thiazolone, 5-(6-quinolinylmethylene)-2-[(2-thienylmethyl)amino]-, (5Z)-
  • (5Z)-5-(quinolin-6-ylmethylidene)-2-(thiophen-2-ylmethylamino)-1,3-thiazol-4-one
  • CS-770
  • Ro 3306 USP/EP/BP
  • 872573-93-8
  • Inhibitors
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