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L-Alanyl-L-Glutamine

L-Alanyl-L-Glutamine Struktur
39537-23-0
CAS-Nr.
39537-23-0
Englisch Name:
L-Alanyl-L-Glutamine
Synonyma:
ALA-GLN;Alu-Gln;ALANYL-GLUTAMINE;N(2)-L-ALANYL-L-GLUTAMINE;DIPEPTIVEN;Ala-Gln-OH;H-ALA-GLN-OH;L-ALANY-L-GLUTAMINE;L-Alanyl-L-Glutamine Alanyl Glutamine;Aln-Gln
CBNumber:
CB9253481
Summenformel:
C8H15N3O4
Molgewicht:
217.22
MOL-Datei:
39537-23-0.mol

L-Alanyl-L-Glutamine Eigenschaften

Schmelzpunkt:
215 °C
Siedepunkt:
615℃
Dichte
1.305±0.06 g/cm3(Predicted)
Dampfdruck
0-1000Pa at 20-313.7℃
FEMA 
4712 | L-ALANYL-L-GLUTAMINE
RTECS-Nr.
MA2275262
Brechungsindex
10 ° (C=5, H2O)
Flammpunkt:
>110°(230°F)
storage temp. 
2-8°C
L?slichkeit
Water (Sparingly)
Aggregatzustand
solution
pka
3.12±0.10(Predicted)
Farbe
White
PH
pH(50g/l, 25℃) : 5.0~6.0
Geruch (Odor)
mild savory
Wasserl?slichkeit
Soluble in water.
JECFA Number
2121
Stabilit?t:
Hygroscopic
InChIKey
HJCMDXDYPOUFDY-AKGZTFGVSA-N
LogP
-4.6 at 22℃ and pH6.3
Oberfl?chenspannung
70mN/m at 1g/L and 20℃
CAS Datenbank
39537-23-0(CAS DataBase Reference)

Sicherheit

Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 23-24/25-36-26
WGK Germany  1
HS Code  29241990

L-Alanyl-L-Glutamine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg. In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration. In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production. Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.

Chemische Eigenschaften

White Solid

Verwenden

A substitute for glutamine in mammalian cell culture media; stable to heat-sterilization.L-Alanyl-L-glutamine is used as a component in pharmaceuticals, cosmetics and food products. It is a stable Gln dipeptide, which protects mice against the jejunal crypt depletion in the setting of dietary protein and fat deficiency. It provides nutritional requirements, improves intestinal health and enhances the immune system. It is also involved in various clinical studies such as cancer treatment, radiation and chemotherapy. It finds application in biotechnology as a component for mammalian cell culture medium. It improves pancreatic beta-cell function, maintaining the mitochondrial metabolism and stimulus-secretion coupling essential for insulin release.

Definition

ChEBI: A dipeptide formed from L-alanyl and L-glutamine residues.

L-Alanyl-L-Glutamine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


L-Alanyl-L-Glutamine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 750)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Chuanghai Biotechnology Co., Ltd
+8617732866630
abby@chuanghaibio.com China 8773 58
Hebei Yanxi Chemical Co., Ltd.
+8618531123677
faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 +86-13131129325
sales1@chuanghaibio.com China 5251 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 988 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021
lisa@kingfinertech.com China 3003 58
Jinan Million Pharmaceutical Co., Ltd
0531-68659554 +8613031714605
info@millionpharm.com China 226 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823
admin@guyunchem.com China 615 58
Hangzhou Hyper Chemicals Limited
+86-0086-57187702781 +8613675893055
info@hyper-chem.com China 295 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126
info@binbobiological.com China 453 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 +86-16264648883
niki@zlchemi.com China 7245 58

39537-23-0()Verwandte Suche:


  • L-Alanyl-L-glutamine(Ala-Gln)
  • L-ALANINE-L-GLUTAMINE
  • L-ALANYL-L-GLUTAMINE
  • glutamine-s
  • Aln-Gln
  • 200 MM ALA-GLN SOLUTION, BIOTECHNOLOGY PERFORMANCE CERTIFIED STABLE GLUTAMINE
  • ALANYL-GLUTAMINE CELL CULTURE TESTED
  • N-L-Alanyl-L-Glutamine
  • L-Alanyl-L-glutamide
  • L-Glutamine, L-alanyl-
  • Glycyl-L-Glutamine (Dipeptiven)
  • DIPETIVEN
  • L-Alanyl-L-Glutamin
  • Glutamine dipeptide
  • Alanyl-glutamine, Glutamine-S
  • Ala-Gln,Alanyl-glutamine, Glutamine-S
  • ALA-GLN(ALANYL-GLUTAMINE)
  • Dipeptiven(L-Alanyl-L-Glutamine)
  • L-alanyl-L-glutamine (Glutamine-S)
  • Dipeptiven H-Ala-Gln
  • (2S)-5-amino-2-[[(2S)-2-aminopropanoyl]amino]-5-keto-valeric acid
  • (2S)-5-amino-2-[[(2S)-2-aminopropanoyl]amino]-5-oxopentanoic acid
  • (2S)-5-azanyl-2-[[(2S)-2-azanylpropanoyl]amino]-5-oxo-pentanoic acid
  • Alanyl-glutaMine(Ala-Gln,GlutaMine-S)
  • (S)-5-aMino-2-((S)-2-aMinopropanaMido)-5-oxopentanoic acid
  • Ala-Glum (L-Alanine-L-glutamine)
  • Ala-Gln-OH≥ 99% (HPLC)
  • Glutamine CAS 39537-23-0
  • Ala-Glum
  • L-Alanyl-L-glutamine >
  • N(2)-L-alanyl-L-glutamine USP/EP/BP
  • Alanyl glutamine USP/EP/BP
  • L-alanine-L-glutamine USP/EP/BP
  • L-Alanyl-L-Glutamine USP/EP/BP
  • Ala-Gln|H-Ala-Gln-OH
  • Alanyl glutamine Bachem-G1210.0001
  • laevo-alanyl-laevo-glutamine
  • Dipeptamin
  • L-Alanyl-L-Glutamine (1012517)
  • H-ALA-GLN-OH
  • DIPEPTIVEN
  • ALANYL-GLUTAMINE
  • ALA-GLN
  • N(2)-L-ALANYL-L-GLUTAMINE
  • Alu-Gln
  • Ala-Gln-OH
  • L-Alanyl-L-Glutamine Alanyl Glutamine
  • L-ALANY-L-GLUTAMINE
  • L-alanyl-L-glutamine/alanine dipeptide/peptide
  • L-Alanyl-L-glutamine, 10 mM in DMSO
  • L-Alanyl-L-glutamine
  • Glutamine-X Solution 200mM, Sterile
  • Stable Glutamine (L-Alanyl-L-Glutamine Solution), 200 mM
  • 39537-23-0
  • 39573-23-0
  • 402135-14-1
  • C8H15N3O4
  • Dipeptides and Tripeptides
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