3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-aminhydrochlorid
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- CAS-Nr.
- 41100-52-1
- Bezeichnung:
- 3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-aminhydrochlorid
- Englisch Name:
- Memantine HCl
- Synonyma:
- Memantine hydrochloride;Namenda;Memantin;3,5-dimethyladamantan-1-amine hydrochloride;3,5-dimethyl-1-aminoadamantane hydrochloride;MENANTINE HYDROCHLORIDE;3,5-dimethyladamantan-1-amine;3,5-DIMETHYL-1-ADAMANTANAMINE HYDROCHLORIDE;D-145;Axura
- CBNumber:
- CB9232635
- Summenformel:
- C12H22ClN
- Molgewicht:
- 215.76
- MOL-Datei:
- 41100-52-1.mol
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3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-aminhydrochlorid Eigenschaften
- Schmelzpunkt:
- 292 °C
- storage temp.
- Inert atmosphere,2-8°C
- L?slichkeit
- Soluble in Water (up to 20 mg/ml)
- Aggregatzustand
- Fine Powder
- Farbe
- White
- Wasserl?slichkeit
- Soluble in water (100mM)
- Merck
- 14,5806
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
- InChI
- InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H
- InChIKey
- LDDHMLJTFXJGPI-UHFFFAOYSA-N
- SMILES
- C12(N)CC3(C)CC(CC(C)(C3)C1)C2.[H]Cl
- CAS Datenbank
- 41100-52-1(CAS DataBase Reference)
3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-aminhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Memantine, a NMDA receptor antagonist, was
co-developed by Forest Laboratories with Merz
Pharmaceuticals and marketed under the trade name
Namenda for the treatment of Alzheimer’s disease in the US
after its approval in October, 2003. This drug has been
available in many European and Asian markets before
getting approval in the US.
Chemische Eigenschaften
Crystalline Solid
Application
Memantine HCl has been used:
- as a media
supplement to serve as a control to study the neuroprotective effects of
erythropoietin in N-methyl-D-aspartate receptor-induced toxicity.
- to intraperitoneally inject experimental animal to study its effect on traumatic injury.
- as a test compound to determine the dynamic range and selectivity of retinal pigment epithelium tissue penetration.
Verwenden
Used as an antiparkinsonian and antispasmodic
Definition
ChEBI: A hydrochloride obtained by reaction of memantine with one equivalent of hydrochloric acid. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Memantine Hydrochloride is a drug used for treating the Alzheimer′s disease by means of reducing abnormal activity in the brain. It can help patients suffering from dementia as it assists them to think more clearly and perform their chores with ease.
Nebenwirkungen
Serious side effects:
Allergic reaction. Symptoms can include:
swelling of your tongue, lips, or face; shortness of breath; skin rash; hives
Hepatitis (inflammation of the liver). Symptoms can include:
yellowing of your skin or the whites of your eyes.
Pancreatitis (inflammation of the pancreas). Symptoms can include:
severe nausea; severe abdominal pain.
Change in mental health. Symptoms can include:
hallucinations; thoughts of suicide.
Congestive heart failure. Symptoms can include:
shortness of breath; swelling in your feet and ankles.
3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-aminhydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-aminhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 731)Lieferanten
41100-52-1(3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-aminhydrochlorid)Verwandte Suche:
- MEMANTINE HCL
- LABOTEST-BB LT00233220
- 1,3-Dimethyl-5-aminoadamantane hydrochloride
- 1,3-DIMETHYLAMINOADAMANTANE HYDROCHLORIDE
- 1-AMINO-3,5-DIMETHYLADAMANTANE HCL
- 1-AMINO-3,5-DIMETHYLADAMANTANE HYDROCHLORIDE
- 1-AMINO-3,4-DIMETHYLADAMANTANE HYDROCHLORIDE
- 3,5-DIMETHYLAMANTADINE HYDROCHLORIDE
- 3,5-DIMETHYL-1-AMINOADAMANTANE HCL
- 3,5-DIMETHYL-1-ADAMANTANAMINE
- 1,3-DiMethyl-5-aMinoadaMantane hydrochloride, 99% 1GR
- D-145
- MeMantine hydrochloride API
- 1-Amino-3,5-dimethyladamantane Hydrochloride
Memantine Hydrochloride
- MEMANTINE HCL(SH)
- Ebony fruit extract
- 3,5-dimethyl-tricyclo[3.3.1.13,7]decan-1-amine,hydrochloride (1:1)
- Memantine HCl (Namenda)
- Axura
- Ebixa
- Ebixia
- Ebixza
- Memantine hydrochloride (JAN/USAN)
- Memantine hydrochloride [USAN]
- Namenda (TN)
- Tricyclo(3.3.1.1(3,7))decan-1-amine, 3,5-dimethyl-, hydrochloride
- Memantine Hydrochloride (150 mg)
- Memantine hydrochloride, >=99%
- Dark Plum Fruit extract
- Menantine HCl
- 3,5-DIMETHYL-TRICYCLO[3.3.1.13,7]DECAN-1-AMINE HYDROCHLORIDE
- AKATINOL
- TIMTEC-BB SBB003390
- Akatinol, 3,5-Dimethyltricyclo-[3,3,1,13,7]decan-1-amine, 3,5-Dimethyl-1-adamantanamine
- 1,3-Dimethyl-5-aminoadamantane
- EMANTINEHYDROCHLORIDE
- MemantinHCl
- 3,5-Dimethyl-1-adamantanamine hydrochloride, 3,5-Dimethylamantadine hydrochloride
- 3,5-Dimethyladamantane-1-amine·hydrochloride
- SUN-Y-7017
- Fructus Mume P.E.
- 1,3-Dimethyl-5-aminoadamantane hydrochloride,99%
- 3,5-Dimethyladamantanamine Hydrochloride
- (3,5-dimethyl-1-adamantyl)amine hydrochloride
- 1,3-Dimethyl-5-aminoadamantane hydrocloride, 99%
- MEMANTINE HCL(SG)
- Fructus Mume extract
- 3,5-Dimethyl-1-adamantanamine hydrochloride, 99%, amantadine derivative
- Memantine hydrochloride 3,5
- Dark Plum Fruit、Smoked Plum、Dark Plum.
- 3,5-Dimethyl-1-adamantanamineHydrochloride>
- D-145 (hydrochloride)
- Memantine hydrochL
- Memantine hydrochloride Solution in Methanol, 100μg/mL
- Memantine HCl USP/EP/BP
- High Purity Memantine Hydrochloride CAS 41100-52-1 in Stock
- Adamantane Impurity 27 HCl
- Memantine Hydrochloride (Secondary standard)
