BIS(4-HYDROXYCINNAMOYL)METHANE
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- CAS-Nr.
- 33171-05-0
- Englisch Name:
- BIS(4-HYDROXYCINNAMOYL)METHANE
- Synonyma:
- BISDEMETHOXY CURCUMIN;CURCUMIN 3;Misdemeanour;Didemethoxycurcumin;BIS-DESMETHOXYCURCUMIN;DEMETHOXYCURCUMIN, BIS-;Bisdemethoxycurcumin(b);(E,E)-BisdeMethoxycurcuMin;Bisdemethoxycurcumin(BDMC);Bis(p-hydroxycinnamoyl)methane
- CBNumber:
- CB9180475
- Summenformel:
- C19H16O4
- Molgewicht:
- 308.33
- MOL-Datei:
- 33171-05-0.mol
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BIS(4-HYDROXYCINNAMOYL)METHANE Eigenschaften
- Schmelzpunkt:
- 221-223 ºC
- Siedepunkt:
- 551.3±45.0 °C(Predicted)
- Dichte
- 1.285
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly, Heated)
- pka
- 8.50±0.46(Predicted)
- Aggregatzustand
- solid
- Farbe
- Orange to Dark Orange
- BRN
- 3149384
- Stabilit?t:
- Light Sensitive
- LogP
- 3.155 (est)
BIS(4-HYDROXYCINNAMOYL)METHANE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Bisdemethoxycurcumin is one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflammatory as well as chemotherapeutic activit
y. Bisdemethoxycurcumin acts as an inhibitor of human pancreatic α-amylase, a target for type-2 diabetes .
Allgemeine Beschreibung
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
Bisdemethoxycurcumin (BDMC) is a derivative or curcumin, and represents one of the major active components of curcumin products isolated from Curcumae sp. BDMC shares similar anti-inflammatory properties with demethoxycurcumin. It inhibits LPS-induced nitric oxide (NO) production and expression of iNOS and COX2 in RAW264.7 cells by blocking NF-kB activation. BDMC also displays unique properties in that it enhances Abeta clearance by upregulating expression MGAT3 and TLR genes. BDMC potently inhibits AKR1B10.
BIS(4-HYDROXYCINNAMOYL)METHANE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
BIS(4-HYDROXYCINNAMOYL)METHANE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 202)Lieferanten
33171-05-0()Verwandte Suche:
- (1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
- PARAPARADIHYDROXYDICINNAMOYLMETHANE
- (E,E)-BisdeMethoxycurcuMin
- (E,E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
- CURCUMIN 3
- DEMETHOXYCURCUMIN, BIS-
- BIS-DESMETHOXYCURCUMIN
- BIS(4-HYDROXYCINNAMOYL)METHANE
- Didemethoxycurcumin
- 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (E,E)-
- Bis(p-hydroxycinnamoyl)methane
- Deleted CAS No: 22608-12-4, 85801-92-9, 91884-88-7, 104024-29-5
- Bisdemethoxycurcumin, 98%, from Zingiber officinale Rosc.
- Bisdemethoxycurcumin(BDMC)
- Bisdemethoxycurcumin(b)
- 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-
- BIS(4-HYDROXYCINNAMOYL)METHANE USP/EP/BP
- Misdemeanour
- BISDEMETHOXY CURCUMIN
- (1E,6E)-Bis(demethoxy)curcumin
- (E,E)-Curcumin III,Bisdemethoxycurcumin,inhibit,(E,E)-Didemethoxycurcumin,Inhibitor,Apoptosis,Autophagy,(E,E)-Bisdemethoxycurcumin
- Bisdemethoxycurcumin/1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-
- 33171-05-0
- 34939-16-0
- Miscellaneous Natural Products
