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ANTI-MONKEY IGG, WHOLE MOLECULE HRP CONJUGATED

ANTI-MONKEY IGG, WHOLE MOLECULE HRP CONJUGATED Struktur
CAS-Nr.
Englisch Name:
ANTI-MONKEY IGG, WHOLE MOLECULE HRP CONJUGATED
Synonyma:
ANTI-MONKEY IGG (WHOLE MOLECULE)-PEROXIDASE;ANTI-MONKEY IGG, WHOLE MOLECULE HRP CONJUGATED;Anti-Monkey IgG (whole molecule)-Peroxidase antibody produced in rabbit
CBNumber:
CB9138168
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-MONKEY IGG, WHOLE MOLECULE HRP CONJUGATED Eigenschaften

storage temp. 
−20°C
Aggregatzustand
buffered aqueous solution
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Sicherheit
P261 Einatmen von Staub vermeiden.
P272 Kontaminierte Arbeitskleidung nicht au?erhalb des Arbeitsplatzes tragen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P333+P313 Bei Hautreizung oder -ausschlag: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

ANTI-MONKEY IGG, WHOLE MOLECULE HRP CONJUGATED Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-Monkey IgG (whole molecule)?Peroxidase antibody produced in rabbit has been used in ELISA of serum samples.

Allgemeine Beschreibung

Monkey IgG is a plasma B cell derived antibody isotype defined by its heavy chain. IgG is the most abundant antibody isotype found in monkey serum. IgG crosses the placental barrier, is a complement activator and binds to the Fc-receptors on phagocytic cells. The level of IgG may vary with the status of disease or infection.
Horseradish Peroxidase (HRP) is an enzyme that catalyzes the conversion of chromogenic substrates such as o-phenylenediamine (OPD), 4-chloro-1-naphthol 3,3′,5,5′-tetramethylbenzidine (TMB), 3,3′-Diaminobenzidine (DAB) or 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS); chemiluminescent substrates such as CPS-3 (enhanced luminal) and fluorogenic substrates such as Ampliflu? Red into detectable chromophores, light-emitters or fluorescers, respectively.

Biochem/physiol Actions

Digestion of IgG by papain results in generation of fragment antigen binding (Fab). Pepsin digestion of IgG results in fragment crystallizable (Fc). Fc regions of IgG antibody have enormous therapeutic potential and are exploited for the development of therapeutic antibodies. IgG1 class is the most abundant and its deficiency results in hypogammaglobulinemia. IgG2 deficiency increases susceptibility to bacterial infections. IgG3 mediates effector functions and IgG4 is associated with asymptomatic infection. The IgG levels in monkey show age related increase. In monkeys, IgG subtypes comprises the predominant antibodies during immune response after hepatitis B surface antigen (HBsAg) vaccination. The human and monkey IgG sequences show divergence only in the hinge region and hence exploited for therapeutic antibody testing.

ANTI-MONKEY IGG, WHOLE MOLECULE HRP CONJUGATED Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-MONKEY IGG, WHOLE MOLECULE HRP CONJUGATED Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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Sigma-Aldrich 021-61415566 800-8193336
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  • ANTI-MONKEY IGG, WHOLE MOLECULE HRP CONJUGATED
  • ANTI-MONKEY IGG (WHOLE MOLECULE)-PEROXIDASE
  • Anti-Monkey IgG (whole molecule)-Peroxidase antibody produced in rabbit
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  • by Label
  • M
  • Monkey Secondary Antibodies and ConjugatesAlphabetical Index
  • OtherSecondary Antibodies
  • Peroxidase
  • Secondary Antibodies
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