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Cefovecin sodium

Cefovecin sodium Struktur
141195-77-9
CAS-Nr.
141195-77-9
Englisch Name:
Cefovecin sodium
Synonyma:
UK287;UK 287;D01681;C13142;074-02;UK-287;UK287,074-02;UK 287,074-02;UK-287,074-02;Cefovecin SodiuM
CBNumber:
CB91260675
Summenformel:
C17H18N5NaO6S2
Molgewicht:
0
MOL-Datei:
141195-77-9.mol

Cefovecin sodium Eigenschaften

storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
InChIKey
QRIBXVGHDLFNNE-RUPIGQPYNA-M
SMILES
[Na+].N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N/OC)=O)C1=O)SCC([C@@H]1CCCO1)=C2C([O-])=O |&1:2,4,23,r|

Sicherheit

Cefovecin sodium Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Cefovecin sodium is a semi-synthetic broad-spectrum antibacterial agent from the cephalosporin class of chemotherapeutic agents. Cefovecin is the non-proprietary designation for (6R,7R)-7- [[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[(2S)-tetrahydro-2-furanyl]-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt.
Cefovecin Sodium is an antibiotic of the cephalosporin class. It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs. Cefovecin Sodium is the first single-dose injectable antibiotic for dogs and cats.

Verwenden

Sodium salt of Cefovecin, a cephalosporin antibiotic used in the treatment of skin conditions in dogs and cats.

Indications

Dogs
Cefovecin sodium is indicated for the treatment of skin infections (secondary superficial pyoderma, abscesses, and wounds) in dogs caused by susceptible strains of Staphylococcus intermedius and Streptococcus canis (Group G).
Cats
Cefovecin sodium is indicated for the treatment of skin infections (wounds and abscesses) in cats caused by susceptible strains of Pasteurella multocida.

Nebenwirkungen

In cats, the most common effects are vomiting, diarrhea, decreased appetite, lethargy, hyperactivity or “acting strange” and inappropriate urination.
In dogs, the most common adverse effects were lethargy, decreased appetite, vomiting, diarrhea, blood in feces, dehydration, and flatulence.

Sicherheit(Safety)

Dogs
CONVENIA administered to healthy four month old dogs at doses of 12 mg/kg (1.5 X), 36 mg/kg (4.5 X), and 60 mg/kg (7.5 X) every seven days by dorsoscapular subcutaneous injections was well-tolerated for a total of 5 doses. Vomiting and diarrhea were seen in all treatment groups, with the incidence of vomiting and the incidence and duration of diarrhea increasing in a dose-related manner. Injection site irritation and transient edema occurred with increasing frequency in a dose-related manner and with repeat injections. Two injection site reactions included a seroma over the shoulder and swelling lasting > 30 days. Dogs dosed at 36 mg/kg had a significant (p = 0.0088) increase in BUN (all means remained within the normal range) compared to the controls. One dog dosed at 60 mg/kg exhibited a glomerulopathy on histopathology, and one dog in this same group had minimal peliosis hepatis. At an exaggerated dose of 180 mg/kg (22.5X) in dogs, CONVENIA caused some injection site irritation, vocalization and edema. Edema resolved within 8-24 hours.
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Cefovecin sodium Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Cefovecin sodium Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 61)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Masteam Bio-tech Co., Ltd.
+86-15200345168 +86-15200345168
bruce.lei@masteam.com CHINA 151 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
ENBRIDGE PHARMTECH CO., LTD.
+8613812269233
tinayang@enbridgepharm.com China 322 58
Shanghai UCHEM Inc.
+862156762820 +86-13564624040
sales@myuchem.com China 7629 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15352 58
Hainan Mike Biomedical Technology Co., Ltd
+86-15120707353 +86-18876637353
tunanmedicine@hotemail.com China 43 58
Wuhan Fortuna Chemical Co., Ltd
+86-027-59207850
info@fortunachem.com China 5975 58
Baoji Guokang Healthchem co.,ltd
+8615604608665 15604608665
dominicguo@gk-bio.com CHINA 9414 58
Alfa Chemistry

Info@alfa-chemistry.com United States 24072 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58

141195-77-9()Verwandte Suche:


  • sodium (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl] amino]-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene- 2-carboxylate
  • Cefovecin SodiuM
  • Ceftrexine sodium
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[(2S)-tetrahydro-2-furanyl]-,sodium salt (1:1), (6R,7R)-
  • 074-02
  • C13142
  • D01681
  • UK 287
  • UK287
  • UK-287
  • UK 287,074-02
  • UK-287,074-02
  • UK287,074-02
  • (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-[(2S)-oxolan-2-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Cefovecin Sodium Salt
  • Cofovecin Sodium
  • Sodium (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-Thiazol-4-Yl)-2-Methoxyiminoacetyl]Amino]-8-Oxo-3-[(2S)-Oxolan-2-Yl]-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
  • 141195-77-9
  • C17H18N5O6S2Na
  • Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
  • 1
  • API
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