4-(Iodomethyl)tetrahydro-2H-pyran
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- CAS-Nr.
- 101691-94-5
- Englisch Name:
- 4-(Iodomethyl)tetrahydro-2H-pyran
- Synonyma:
- 4-(iodomethyl)oxane;4-IODOMETHYLTETRAHYDROPYRAN;4-(Iodomethyl)tetrahydropyrane;4-(IODOMETHYL)TETRAHYDRO-2H-PYRAN;(4-TETRAHYDROPYRANYL)METHYL IODIDE;Tetrahydro-4-(iodomethyl)-2H-pyran;4-(Iodomethyl)tetrahydro-2H-pyrane;2H-Pyran, tetrahydro-4-(iodomethyl)-
- CBNumber:
- CB9120260
- Summenformel:
- C6H11IO
- Molgewicht:
- 226.06
- MOL-Datei:
- 101691-94-5.mol
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4-(Iodomethyl)tetrahydro-2H-pyran Eigenschaften
- Siedepunkt:
- 229.1±13.0 °C(Predicted)
- Dichte
- 1.645±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H314 |
Verursacht schwere Ver?tzungen der Haut und schwere Augensch?den. |
?tzwirkung auf die Haut |
Kategorie 1B |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501 |
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| Sicherheit |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P363 |
Kontaminierte Kleidung vor erneutem Tragen waschen. |
| P405 |
Unter Verschluss aufbewahren. |
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4-(Iodomethyl)tetrahydro-2H-pyran Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
4-(Iodomethyl)tetrahydro-2H-pyran is prepared from 4-(methanesulfonyloxymethyl)tetrahydropyran by heating and refluxing under conditions of reaction with sodium iodide in acetone. The specific method of operation is described below:
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Preparation: A mixture of Preparation (328g, 1.69mol) and sodium iodide (507g, 3.4mol) in acetone (3.3L) was refluxed for 4h. TLC (diethyl ether) showed significant mesylate remaining so further sodium iodide (127g, 0.65mol) was added and reflux continued for 16h. The mixture was cooled and filtered. The resulting cake was washed with acetone, dried, and11then partitioned between diethyl ether (800mL) and water (800mL). The aqueous phase was re-extracted with diethyl ether (200mL), the ether extracts combined and washed with 10% sodium thiosulphate solution (300mL) which decolourised the extract. Final washing with water (300mL), drying (MgS04) and then removal of the solvent provided the 4-(IODOMETHYL)TETRAHYDRO-2H-PYRAN (365g, 92% yield).
4-(Iodomethyl)tetrahydro-2H-pyran Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-(Iodomethyl)tetrahydro-2H-pyran Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 106)Lieferanten
- 4-(IODOMETHYL)TETRAHYDRO-2H-PYRAN
- 4-IODOMETHYLTETRAHYDROPYRAN
- (4-TETRAHYDROPYRANYL)METHYL IODIDE
- 4-(Iodomethyl)tetrahydropyrane
- 4-(iodomethyl)oxane
- 2H-Pyran, tetrahydro-4-(iodomethyl)-
- 4-(Iodomethyl)tetrahydro-2H-pyrane
- Tetrahydro-4-(iodomethyl)-2H-pyran
- 101691-94-5
