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ANTI-HSNF5/INI1

ANTI-HSNF5/INI1 Struktur
CAS-Nr.
Englisch Name:
ANTI-HSNF5/INI1
Synonyma:
ANTI-HSNF5/INI1;Anti-hSNF5/INI1 antibody produced in rabbit
CBNumber:
CB9119725
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-HSNF5/INI1 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous solution

Sicherheit

S-S?tze: 23-24/25
WGK Germany  -

ANTI-HSNF5/INI1 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Anti-hSNF5/INI1 antibody produced in rabbit has been used in microarray and immunofluorescence.

Allgemeine Beschreibung

INI1/SNF5, also known as SWItch/sucrose non-fermentable (SWI/SNF) related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1, is encoded by the gene mapped to human chromosome 22q11.2. This gene codes for an essential component of chromatin-remodelling SWI/SNF multiprotein complexes.

Biochem/physiol Actions

INI1/sucrose non-fermentable 5 (SNF5) plays a vital role in transcriptional activation of inducible genes through chromatin remodelling. hSNF5/INI1 interacts with the protooncogene c-Myc and the SWI complex is necessary for c-Myc mediated transactivation. hSNF5 displays properties of a tumor-suppressor gene, as sporadic rhabdoid tumors show biallelic loss-of-function mutations and germline mutations confer an autosomal-dominant syndrome that predisposes patients to a variety of rhabdoid cancers. Loss of function mutations of the gene is associated with the pathogenesis of aggressive pediatric cancer and epithelioid schwannoma. SNF5 interacts with E1 protein of human papillomavirus (HPV) and thus, enhances the efficiency of HPV DNA replication.

ANTI-HSNF5/INI1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-HSNF5/INI1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 3)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80

  • Anti-hSNF5/INI1 antibody produced in rabbit
  • ANTI-HSNF5/INI1
  • Alphabetical Index
  • Antibodies for EpigeneticsAntibodies for Gene Regulation and Expression
  • Antibodies for Gene Regulation and Expression
  • Antibodies in Chromatin Remodeling
  • Antibodies to Transcription RegulatorsAntibodies
  • Functional Profiling of Stem Cells
  • H
  • Stem Cell Biology
  • Antibodies to Remodeling ComplexCell Biology
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