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Clostebol

Clostebol Struktur
1093-58-9
CAS-Nr.
1093-58-9
Bezeichnung:
Clostebol
Englisch Name:
Clostebol
Synonyma:
CLOSTEBOL;Cholostebol;17β-Clostebol;Chlortestosterone;Clostebol VETRANAL;Clostebol Standard;Clostebol USP/EP/BP;C11691600 Clostebol;ClostebolAcetateBase;4-CHLOROTESTOSTERONE
CBNumber:
CB8730750
Summenformel:
C19H27ClO2
Molgewicht:
322.87
MOL-Datei:
1093-58-9.mol

Clostebol Eigenschaften

Schmelzpunkt:
188-190°
alpha 
D20 +148° (CHCl3)
Siedepunkt:
448.4±45.0 °C(Predicted)
Dichte
1.0514 (estimate)
L?slichkeit
DMF: 20 mg/mL; DMSO: 30 mg/mL; DMSO:PBS (pH 7.2) (1:10): 0.09 mg/mL; Ethanol: 20 mg/mL
Aggregatzustand
A crystalline solid
pka
14.99±0.70(Predicted)
CAS Datenbank
1093-58-9(CAS DataBase Reference)
NIST chemische Informationen
4-Chloro-17beta-hydroxyandrost-4-en-3-one(1093-58-9)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 40
S-S?tze: 36/37
DEA Controlled Substances CSCN: 4000
CSA SCH: Schedule III
NARC: No
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H351 Kann vermutlich Krebs verursachen. Karzinogenit?t Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P281 Vorgeschriebene pers?nliche Schutzausrüstung verwenden.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Clostebol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R40:Verdacht auf krebserzeugende Wirkung.

S-S?tze Betriebsanweisung:

S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.

Beschreibung

Clostebol (Item No. 21168) is an analytical reference standard that is categorized as an androgenic anabolic steroid. Clostebol is a chlorinated form of testosterone (Item Nos. 15645 | ISO60154) that has been used as an athletic performance enhancer and to fatten cattle. It is also detectible in urine. Formulations containing clostebol have been used to treat osteoporosis, anorexia, and certain types of liver disease. Clostebol is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.

Verwenden

Clostebol is an anabolic steroid. This is a controlled substance.

Synthese

Clostebol can be synthesized from 4,5-Epoxy-androstan-17β-ol-3-one by acidification with 25% hydrochloric acid.
Procedure:8.50 g epoxide (4,5-Epoxy-androstan-17β-ol-3-one) was dissolved in 150 ml Acetone and treated with 14 ml of 25% hydrochloric acid. An immediate color shift of the reaction mixture from light yellow to deep blue can be observed. After stirring for 30 h at room temperature, a complete conversion of the epoxide (4,5-Epoxy-androstan-17β-ol-3-one) can be monitored by TLC. The reaction mixture was diluted with 400 ml water, leading to the formation of a blue-black solid precipitating from the solution. After evaporation of acetone, the remaining aqueous solution was extracted several times with 200 ml dichloromethane. The combined organic extracts were washed with saturated sodium bicarbonate solution and sodium chloride solution before drying over magnesium sulfate. The crude product was chromatographed on silica gel by using hexane-ethyl acetat (1:1) and followed by a recrystallization from acetone. The isolated product Clostebol was obtained as yellowish crystals (4.50 g; 51%).

Clostebol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Clostebol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 45)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
PT CHEM GROUP LIMITED
+86-85511178; +86-85511178;
peter68@ptchemgroup.com China 35425 58
Apeloa production Co.,Limited
+8619933239880
admin@apcl.com.cn China 852 58
Mainchem Co., Ltd. +86-0592-6210733
sale@mainchem.com China 32343 55
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2123 70
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
sales@rrkchem.com China 57423 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
ShangHai Anpel Co, Ltd. 18501792038; 18501792038
shanpel@anpel.com.cn China 9611 58
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 15900491054
info@scrbio.com China 10329 58

1093-58-9(Clostebol)Verwandte Suche:


  • 4-Chloro-17beta-hydroxyandrost-4-en-3-one
  • Androst-4-en-3-one, 4-chloro-17-hydroxy-, (17beta)-
  • 4-ANDROSTEN-4-CHLORO-17-BETA-OL-3-ONE
  • 4-CHLOROTESTOSTERONE
  • 4-CHLOROTESTOSTERONE ALCOHOL
  • CLOSTEBOL
  • Clostebol VETRANAL
  • ClostebolAcetateBase
  • 4-Chloro-17b-hydroxy-4-androsten-3-one
  • 4-Chloro-17β-hydroxy-4-androsten-3-one, 4-Chlorotestosterone
  • Androst-4-en-3-one, 4-chloro-17-hydroxy-, (17b)-
  • 17β-Clostebol
  • 17β-Hydroxy-4-chloroandrosta-4-ene-3-one
  • 4-Chloro-17β-hydroxyandrost-4-en-3-one
  • Chlortestosterone
  • Cholostebol
  • Chlorotestosteronum acetate
  • (8R,9S,10R,13S,14S,17S)-4-chloro-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • (17β)-4-Chloro-17-hydroxyandrost-4-en-3-one
  • 4-Chloro-3-oxo-17β-hydroxyandrost-4-ene
  • Clostebol Solution, 100ppm
  • Clostebol Acetate Impurity 1
  • Clostebol Standard
  • Androst-4-en-3-one, 4-chloro-17-hydroxy-, (17β)-
  • Clostebol USP/EP/BP
  • Clostebol Raw Powder
  • 4-ANDROSTEN-4-CHLORO-17β-OL-3-ONE
  • C11691600 Clostebol
  • Clostebol 100 μg/ml Acetonitrile
  • 1093-58-9
  • C19H27ClO2
  • Steroid and Hormone
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