Pomalidomide-PEG3-CO2H Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Protein degrader builiding block Pomalidomide-PEG₃-CO₂H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

Pomalidomide-PEG3-CO2H Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Pomalidomide-PEG3-CO2H Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	7629	58
Alfa Chemistry		Info@alfa-chemistry.com	United States	24072	58
Nanjing Bicbiotechnology Co., Ltd	+86-2552131256 +86-18251840740	sales@bicbiotech.com	China	5994	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068 +86-15680926068	1924344760@confluore.cn	China	2996	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Suzhou ARTK Medchem Co., Ltd.	+86-512-68323658 +86-18168183658	sales1@artkmedchem.com	China	39004	58
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7195	65
ChemShuttle, Inc.	0510-83588313-802 18800520310;	sales@chemshuttle.com	China	3002	62

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• POMALIDOMIDE-PEG 3-CO 2 H
• Pomalidomide-PEG3-CO2H
• 3-[2-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]propanoic acid
• Propanoic acid, 3-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]-
• Pomalidomide-PEG3-CO2H >=95%
• Pomalidomide-PEG3-COOH
• 3-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)propanoic acid
• Thalidomide-NH-PEG3-propionic acid
• Thalidomide-NH-PEG3-C2-COOH
• 3-[2-[2-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]ethoxy]ethoxy]propanoic Acid
• Thalidomide-4-NH-PEG3-C2-COOH
• Poma-PEG3-COOH
• Pomalidomide 4'-PEG3-acid
• 3-{2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)ethoxy]ethoxy}propanoic acid
• 2138440-82-9
• C22H27N3O9
• peg