CAPECITABINE-D11
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- CAS-Nr.
- 1132662-08-8
- Englisch Name:
- CAPECITABINE-D11
- Synonyma:
- Xeloda-d11;Captabin-d11;Capiibine-d11;Ro 09-1978-d11;Capecytabine-d11;Capecitibine-d11;CAPECITABINE-D11;Ro 09-1978/000-d11;[2H11]-Capecitabine;2’-O-(5’-Deoxy-?-D-ribofuranosyl) Capecitabine-d11
- CBNumber:
- CB8457758
- Summenformel:
- C15H13D11FN3O6
- Molgewicht:
- 372.43
- MOL-Datei:
- Mol file
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CAPECITABINE-D11 Eigenschaften
- Schmelzpunkt:
- 45-50°C
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly, Heated)
- Aggregatzustand
- Solid
- Farbe
- Off-White to Pale Yellow
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
CAPECITABINE-D11 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Capecitabine-d
11 is intended for use as an internal standard for the quantification of capecitabine by GC- or LC-MS. Capecitabine is a prodrug form of 5-fluorouracil (5-FU). It is converted to 5-FU
via several enzymatic steps beginning in the liver and ending with conversion in tumor tissue by thymidine phosphorylase, an enzyme that is more concentrated in tumor tissue compared with normal tissue. Capecitabine is cytotoxic only at high concentrations in Scaber, SIHA, and MKN45 cells (IC
50s = 97, 578, and 994 μM, respectively) and is inactive in a variety of cancer cell lines, including COLO 205, HCT116, and MCF-7 cells (IC
50s = >1,000 μM).
Chemische Eigenschaften
Off-White Powder
Verwenden
An isotopically labelled antineoplastic agent. A prodrug of Doxifluridine (D556750).
CAPECITABINE-D11 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
CAPECITABINE-D11 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 51)Lieferanten
- 5'-Deoxy-5-fluoro-N-[(pentyl-d11-oxy)carbonyl]cytidine
- Capecitibine-d11
- Capecytabine-d11
- Capiibine-d11
- Captabin-d11
- Ro 09-1978/000-d11
- Ro 09-1978-d11
- Xeloda-d11
- [1-(5-Deoxy-α-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyriMidinyl]carbaMic Acid Pentyl-11 Ester
- 5'-DEOXY-5-FLUORO-N-[(PENTYLOXY)CARBONYL]CYTIDINE-D11
- CAPECITABINE-D11
- [2H11]-Capecitabine
- Capecitabine D11Q: What is
Capecitabine D11 Q: What is the CAS Number of
Capecitabine D11 Q: What is the storage condition of
Capecitabine D11 Q: What are the applications of
Capecitabine D11
- 2’-O-(5’-Deoxy-?-D-ribofuranosyl) Capecitabine-d11
- 1132662-08-8
- C15H11D11FN3O6
- Isotope Labelled Compounds
- Bases & Related Reagents
- Intermediates & Fine Chemicals
- Isotope Labeled Compounds
- Nucleotides
- Pharmaceuticals
