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(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Struktur
681490-95-9
CAS-Nr.
681490-95-9
Englisch Name:
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
Synonyma:
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole;(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate;1H-Imidazole-1-propanol, 2-chloro-β-hydroxy-β-methyl-4-nitro-, 1-(4-nitrobenzoate), (βR)-
CBNumber:
CB83154144
Summenformel:
C14H13ClN4O7
Molgewicht:
384.73
MOL-Datei:
681490-95-9.mol

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Eigenschaften

Schmelzpunkt:
122-123 °C(Solv: ethyl acetate (141-78-6); isopropyl ether (108-20-3))
Siedepunkt:
638.9±65.0 °C(Predicted)
Dichte
1.58±0.1 g/cm3(Predicted)
L?slichkeit
Chloroform, DCM
Aggregatzustand
Solid
pka
12.81±0.29(Predicted)
Farbe
Off-White

Sicherheit

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

DE-7

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 9)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Lynnchem 86-(0)29-85992781 17792393971
 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890
 info@novachemistry.com United Kingdom 4381 58
Beijing xinyanhui pharmaceutical research and development co., LTD 13969155946
 1461866103@qq.com China 16111 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q
 meishipharma@126.com China 20033 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 18162595016; 18162595016
 3287908757@qq.com China 9122 58
4008-099-669
 23419001name@qq.com CHINA 73043 58
  • (R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
  • (R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate
  • 1H-Imidazole-1-propanol, 2-chloro-β-hydroxy-β-methyl-4-nitro-, 1-(4-nitrobenzoate), (βR)-
  • 681490-95-9
  • C14H13ClN4O7
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