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Oclacitinib maleate

Oclacitinib maleate Struktur
1640292-55-2
CAS-Nr.
1640292-55-2
Englisch Name:
Oclacitinib maleate
Synonyma:
PF-03394197 maleate;VQIGDTLRBSNOBV-DYXOGNCHSA-N;N-Methyl-1-[trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl]methanesulfonamide Maleate;trans-N-methyl-1-(4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide maleate
CBNumber:
CB83126644
Summenformel:
C19H27N5O6S
Molgewicht:
453.51258
MOL-Datei:
1640292-55-2.mol

Oclacitinib maleate Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
Farbe
White to Off-White
InChIKey
VQIGDTLRBSNOBV-BTJKTKAUSA-N

Sicherheit

Oclacitinib maleate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Oclacitinib Maleate is a novel Janus kinase (JAK) inhibitor with activity against cytokines involved in allergy (1,2).

Biologische Aktivit?t

Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC50 's ranging from 36 to 249 nM. 

Oclacitinib maleate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Oclacitinib maleate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 47)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hpets Biotech Company (Chongqing) Co.,ltd
+8613340353813
info@hanpets.com China 26 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc.
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marketing@targetmol.com United States 32161 58
InvivoChem
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sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58
Jinan Chenghui Shuangda biological Co., LTD 0531-58897003 15550412551
market@jnchsd.com China 217 62
BOC Sciences 1-631-485-4226; 16314854226
info@bocsci.com United States 14055 65
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652
sales@meilune.com China 4727 58

  • VQIGDTLRBSNOBV-DYXOGNCHSA-N
  • PF-03394197 maleate
  • trans-N-methyl-1-(4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide maleate
  • N-Methyl-1-[trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl]methanesulfonamide Maleate
  • 1640292-55-2
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