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3,5,14-Trihydroxy-19-oxocard-20-(22)-enolid, (3 beta, 5 beta)-

STROPHANTHIDIN Struktur
66-28-4
CAS-Nr.
66-28-4
Bezeichnung:
3,5,14-Trihydroxy-19-oxocard-20-(22)-enolid, (3 beta, 5 beta)-
Englisch Name:
STROPHANTHIDIN
Synonyma:
corchorin;cynotoxin;nsc-86078;Corcholin;cyanotoxin;Apocymarin;cymarigenin;Corchotoxin;CYMARIGENEN;apocynamarin
CBNumber:
CB8280598
Summenformel:
C23H32O6
Molgewicht:
404.5
MOL-Datei:
66-28-4.mol

3,5,14-Trihydroxy-19-oxocard-20-(22)-enolid, (3 beta, 5 beta)- Eigenschaften

Schmelzpunkt:
169°C
alpha 
D25 +43.1° (c = 2.8 in methanol)
Siedepunkt:
446.1°C (rough estimate)
Dichte
1.432±0.06 g/cm3 (20 ºC 760 Torr)
Brechungsindex
1.4593 (estimate)
storage temp. 
-20°C
L?slichkeit
ethanol: complete50mg/mL, clear, colorless to yellow
pka
13.92±0.70(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white
Optische Aktivit?t
+43.125 (c 2.8, methanol)

Sicherheit

Kennzeichnung gef?hrlicher T+
R-S?tze: 26/27/28
S-S?tze: 22-36/37/39-45
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
RTECS-Nr. FH5425000
Toxizit?t LD100 i.v. in cats: 0.337 mg/kg (Graebner, Geisel)

3,5,14-Trihydroxy-19-oxocard-20-(22)-enolid, (3 beta, 5 beta)- Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Verwenden

Strophanthidin was used to synthesize acetylstrophanthidin and the effect on neurotransmitter release from dog saphenous vein was studied.3

Allgemeine Beschreibung

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Strophanthidin is a cardiotonic steroid that elevates the activity of Na+/K+-ATPase in cardiac myocytes.1 It decreases the potassium content and raises the sodium content in rabbit renal cortex slices.2

3,5,14-Trihydroxy-19-oxocard-20-(22)-enolid, (3 beta, 5 beta)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Cymarin

Downstream Produkte

α-D-Glucopyranose, 6-O-β-D-glucopyranosyl- D-Glucose 3β,5,14β,21-Tetrahydroxy-24-nor-5β-chol-20(22)-ene-19,23-dioic acid γ-lactone

3,5,14-Trihydroxy-19-oxocard-20-(22)-enolid, (3 beta, 5 beta)- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 72)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Haibo Biotechnology Co., Ltd 		+undefined18602966907
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TargetMol Chemicals Inc.
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Huzhou ZhanShu Biotechnology Co.,Ltd 0572-8889530 18167260939
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Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259108 18621169109
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Beijing HwrkChemical Technology Co., Ltd 010-89508211 18501085097
 sales.bj@hwrkchemical.com China 8418 55
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277
 marketing_china@spectrumchemical.com China 9658 60

66-28-4(3,5,14-Trihydroxy-19-oxocard-20-(22)-enolid, (3 beta, 5 beta)-)Verwandte Suche:

  • 19-oxo-cardogenen-(20:22)-triol-(3-beta,5,14)
  • 3,5,14-trihydroxy-19-oxo-,(3-beta,5-beta)-card-20(22)-enolid
  • 3,5,14-trihydroxy-19-oxocard-20(22)-enolide
  • 3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolid
  • 3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolide
  • 3-beta,5,14-trioxy-19-oxo-carden-(20:22)-olid
  • 3-beta,5,14-trioxy-19-oxo-digen-(20:22)-olid
  • 5-beta-hydroxy-19-oxodigitoxigenin
  • antibioticxs-89
  • apocynamarin
  • convallatoxigenin
  • corchorgenin
  • corchorin
  • corchosideaaglycon
  • corchsularin
  • cyanotoxin
  • cymarigenin
  • cynotoxin
  • erysimupicrone
  • erysimupikron
  • k-strophanthidine
  • nsc-86078
  • strophanthidine
  • (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
  • (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-17-(5-keto-2H-furan-3-yl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
  • STIGMASTANOL(SH)
  • Strophanthidin,3β,5,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide, Cymarigenen, K-Strophanthidin
  • Strophantidin
  • 3β5,14-Trihydroxy-19-oxo-5β20(22)-cardenolide
  • (3beta,5beta)-3,5,14-trihydroxy-19-oxocard-20(22)-enolide
  • 3β,5,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide, Cymarigenen, K-Strophanthidin
  • Corcholin
  • 20(22)-cardenolide
  • 3β,5,14-Trihydroxy-19-oxo-5β
  • Corchorogenin
  • Corchotoxin
  • STROPHANTHIDIN K
  • STROPHANTHIDIN
  • K-STROPHANTHIDIN
  • CYMARIGENEN
  • 5BETA,20[22]-CARDENOLIDE-19-ONE-3BETA,5,14-TRIOL
  • 3BETA,5,14-TRIHYDROXY-19-OXO-5BETA,20[22]-CARDENOLIDE
  • Apocymarin
  • Card-20(22)-enolide,3,5,14-trihydroxy-19-oxo-, (3b,5b)-
  • Card-20(22)-enolide, 3,5,14-trihydroxy-19-oxo-, (3β,5β)-
  • Sodium potassium pump,Na+/K+ ATPase,cardiac,naturally,available,systolic,glycoside,diastolic,Strophanthidin,inhibit,sarcolemmal,Inhibitor
  • Card-20(22)-enolide, 3,5,14-trihydroxy-19-oxo-, (3β,5β)-
  • Strophanthidine-RM
  • 66-28-4
  • Sterol Lipids
  • Aldehydes
  • Biochemicals and Reagents
  • Building Blocks
  • C13-C60
  • Carbonyl Compounds
  • Chemical Synthesis
  • Conjugates
  • Lipids
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