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6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine

6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Struktur
CAS-Nr.
Englisch Name:
6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine
Synonyma:
Ro 106-9920-d5;6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine
CBNumber:
CB82623274
Summenformel:
C10H2D5N5OS
Molgewicht:
250.29128889
MOL-Datei:
Mol file

6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Eigenschaften

Sicherheit

6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Labelled Ro 106-9920 (R637500). Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS.

6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 8)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60

  • 6-[(Phenyl-d5)sulfinyl]tetrazolo[1,5-b]pyridazine
  • Ro 106-9920-d5
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